Yoo Dong Hyun, Kang Mo-Yeol, Paek Domyung, Min Bokki, Cho Sung-Il
Department of Occupational and Environmental Medicine, Graduate School of Public Health and Institute of Health and Environment, Seoul National University, Gwanak-ro 1, Seoul 151-742, Gwanak-gu, Republic of Korea.
Department of Preventive Medicine, School of Medicine, Seoul National University, Daehakro 103, Seoul 110-799, Jongno-gu, Republic of Korea.
Ann Occup Environ Med. 2014 Sep 3;26:25. doi: 10.1186/s40557-014-0025-0. eCollection 2014.
Many studies have reported an association between overwork and hypertension. However, research on the health effects of long working hours has yielded inconclusive results. The objective of this study was to identify an association between overtime work and hypertension in wage workers 45 years and over of age using prospective data.
Wage workers in Korea aged 45 years and over were selected for inclusion in this study from among 10,254 subjects from the Korean Longitudinal Study of Ageing. Workers with baseline hypertension and those with other major diseases were excluded. In the end, a total of 1,079 subjects were included. A Cox proportional hazards model was used to calculate hazard ratios and adjust for baseline characteristics such as sex, age, education, income, occupation, form of employment, body mass index, alcohol habit, smoking habit, regular exercise, and number of working days per week. Additional models were used to calculate hazard ratios after gender stratification.
Among the 1,079 subjects, 85 workers were diagnosed with hypertension during 3974.2 person-months. The average number of working hours per week for all subjects was 47.68. The proportion of overtime workers was 61.0% (cutoff, 40 h per week). Compared with those working 40 h and less per week, the hazard ratio of subjects in the final model, which adjusted for all selected variables, working 41-50 h per week was 2.20 (95% confidence interval [CI], 1.19-4.06), that of subjects working 51-60 h per week was 2.40 (95% CI, 1.07-5.39), and that of subjects working 61 h and over per week was 2.87 (95% CI, 1.33-6.20). In gender stratification models, the hazard ratio of the females tended to be higher than that of the males.
As the number of working hours per week increased, the hazard ratio for diagnosis of hypertension significantly increased. This result suggests a positive association between overtime work and the risk of hypertension.
许多研究报告了过度劳累与高血压之间的关联。然而,关于长时间工作对健康影响的研究结果尚无定论。本研究的目的是利用前瞻性数据确定45岁及以上工薪族的加班工作与高血压之间的关联。
从韩国老龄化纵向研究的10254名受试者中选取45岁及以上的工薪族纳入本研究。排除基线患有高血压和其他重大疾病的工人。最终,共纳入1079名受试者。采用Cox比例风险模型计算风险比,并对性别、年龄、教育程度、收入、职业、就业形式、体重指数、饮酒习惯、吸烟习惯、定期锻炼和每周工作日数等基线特征进行调整。在性别分层后使用额外的模型计算风险比。
在1079名受试者中,85名工人在3974.2人月期间被诊断为高血压。所有受试者每周平均工作小时数为47.68。加班工人的比例为61.0%(临界值为每周40小时)。与每周工作40小时及以下的人相比,在调整了所有选定变量的最终模型中,每周工作41 - 50小时的受试者的风险比为2.20(95%置信区间[CI],1.19 - 4.06),每周工作51 - 60小时的受试者的风险比为2.40(95%CI,1.07 - 5.39),每周工作61小时及以上的受试者的风险比为2.87(95%CI,1.33 - 6.20)。在性别分层模型中,女性的风险比往往高于男性。
随着每周工作小时数的增加,高血压诊断的风险比显著增加。这一结果表明加班工作与高血压风险之间存在正相关。