Seyyedebrahimi ShadiSadat, Khodabandehloo Hadi, Nasli Esfahani Ensieh, Meshkani Reza
Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Diabetes Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Islamic Republic of Iran.
Acta Diabetol. 2018 Oct;55(10):1087. doi: 10.1007/s00592-018-1160-9.
Oxidative stress plays a pivotal role in the pathogenesis of type 2 diabetes (T2D). In vitro and animal studies have shown that resveratrol exerts an antioxidant effect, but clinical trials addressing this effect in patients with T2D are limited. The aim of this study was to determine whether resveratrol supplementation affects oxidative stress markers in a randomized, placebo-controlled, double-blind clinical trial.
氧化应激在2型糖尿病（T2D）的发病机制中起关键作用。体外和动物研究表明，白藜芦醇具有抗氧化作用，但针对T2D患者这一作用的临床试验有限。本研究的目的是在一项随机、安慰剂对照、双盲临床试验中确定补充白藜芦醇是否会影响氧化应激标志物。
