Jackson R, Addison A B, Prinsley P R
Department of ENT,James Paget University Hospital,Great Yarmouth,UK.
Department of ENT,West Suffolk Hospital,Bury Saint Edmunds,UK.
J Laryngol Otol. 2018 Jul;132(7):575-578. doi: 10.1017/S0022215118000890. Epub 2018 Jun 18.
Cholesteatoma is widely considered to be more aggressive in children than adults, yet few studies have directly compared the operative findings and surgical outcomes between these two groups. This study aimed to assess differences between childhood and adult cholesteatoma.
The operative caseload of a single consultant surgeon was reviewed between January 2006 and May 2017 using the online Common Otology Audit database. Extracted data were categorised according to patient age (children, aged below 16 years, and adults, aged 16 years or over) and compared.
This study included data from 71 operations on children and 281 operations on adults, performed for cholesteatoma. Childhood cholesteatoma demonstrated significantly more extension (into the sinus tympani, mastoid antrum and mastoid air cells) and ossicular erosion (of the malleus, incus and stapes superstructure) compared to adults. No significant differences were seen in revision rates, post-operative complications or hearing gain.
Childhood cholesteatoma was more extensive and destructive compared to adults, representing a more aggressive disease in this cohort.
胆脂瘤在儿童中通常被认为比成人更具侵袭性，但很少有研究直接比较这两组患者的手术发现和手术结果。本研究旨在评估儿童胆脂瘤和成人胆脂瘤之间的差异。
使用在线普通耳科学审计数据库回顾了2006年1月至2017年5月期间一位顾问外科医生的手术病例量。提取的数据根据患者年龄（16岁以下儿童和16岁及以上成人）进行分类并比较。
本研究纳入了71例儿童胆脂瘤手术和281例成人胆脂瘤手术的数据。与成人相比，儿童胆脂瘤的扩展（进入鼓室窦、乳突窦和乳突气房）和听骨侵蚀（锤骨、砧骨和镫骨上部结构）更为明显。在翻修率、术后并发症或听力改善方面未观察到显著差异。
与成人相比，儿童胆脂瘤范围更广且更具破坏性，在这一队列中代表一种更具侵袭性的疾病。
