USC Institute of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA.
USC Institute of Urology, USC/Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA.
Urol Oncol. 2019 Mar;37(3):193-200. doi: 10.1016/j.urolonc.2018.05.005. Epub 2018 Jun 15.
Significant evidence exists regarding the diagnostic and therapeutic roles of pelvic lymph node dissection at the time of radical cystectomy for patients with bladder cancer. Despite this, lymphadenectomy for bladder cancer is still underutilized and even where performed, controversies exist in regard to what defines an adequate dissection and whether or not the indications for lymphadenectomy have changed now that we are firmly entrenched in the neoadjuvant chemotherapy era. A comprehensive literature review was performed to touch on these important issues and highlight future directions and current trials that will soon provide more clarity for surgeons and patients dealing with bladder cancer.
大量证据表明，在膀胱癌根治性膀胱切除术中进行盆腔淋巴结清扫具有诊断和治疗作用。尽管如此，膀胱癌淋巴结清扫术的应用仍不充分，即使在进行淋巴结清扫术的情况下，对于什么是充分的清扫以及在我们已经坚定地进入新辅助化疗时代的情况下，淋巴结清扫术的适应证是否已经改变，仍存在争议。本文对这些重要问题进行了全面的文献回顾，强调了未来的方向和当前的试验，这些试验将很快为处理膀胱癌的外科医生和患者提供更清晰的认识。
