Rayner Jenna E, Laino Antonia M, Nufer Kaitlin L, Adams Laura, Raphael Anthony P, Menzies Scott W, Soyer H Peter
Dermatology Research Centre, The University of Queensland, The University of Queensland Diamantina Institute, Brisbane, QLD, Australia.
Dermatology Department, Princess Alexandra Hospital, Brisbane, QLD, Australia.
Front Med (Lausanne). 2018 May 23;5:152. doi: 10.3389/fmed.2018.00152. eCollection 2018.
Melanoma incidence continues to increase across many populations globally and there is significant mortality associated with advanced disease. However, if detected early, patients have a very promising prognosis. The methods that have been utilized for early detection include clinician and patient skin examinations, dermoscopy (static and sequential imaging), and total body photography via 2D imaging. Total body photography has recently witnessed an evolution from 2D imaging with the ability to now create a 3D representation of the patient linked with dermoscopy images of individual lesions. 3D total body photography is a particularly beneficial screening tool for patients at high risk due to their personal or family history or those with multiple dysplastic naevi-the latter can make monitoring especially difficult without the assistance of technology. In this perspective, we discuss clinical examples utilizing 3D total body photography, associated advantages and limitations, and future directions of the technology. The optimal system for melanoma screening should improve diagnostic accuracy, be time and cost efficient, and accessible to patients across all demographic and socioeconomic groups. 3D total body photography has the potential to address these criteria and, most importantly, optimize crucial early detection.
全球许多人群中黑色素瘤的发病率持续上升，晚期疾病会导致显著的死亡率。然而，如果能早期发现，患者的预后非常乐观。用于早期检测的方法包括临床医生和患者的皮肤检查、皮肤镜检查（静态和连续成像）以及通过二维成像进行全身摄影。全身摄影最近经历了从二维成像到现在能够创建与单个病变的皮肤镜图像相关联的患者三维模型的演变。三维全身摄影对于因个人或家族病史而处于高风险的患者，或者对于那些有多个发育异常痣的患者来说，是一种特别有益的筛查工具——对于后者，如果没有技术辅助，监测会特别困难。从这个角度出发，我们讨论了利用三维全身摄影的临床实例、相关的优点和局限性以及该技术的未来发展方向。用于黑色素瘤筛查的最佳系统应提高诊断准确性、具有时间和成本效益，并且所有人口统计学和社会经济群体的患者都能使用。三维全身摄影有潜力满足这些标准，最重要的是，优化关键的早期检测。
