Dannals R F, Ravert H T, Frost J J, Wilson A A, Burns H D, Wagner H N
Int J Appl Radiat Isot. 1985 Apr;36(4):303-6. doi: 10.1016/0020-708x(85)90089-4.
Carfentanil, a potent opiate receptor agonist, was labeled with 11C for in vivo studies using positron emission tomography. This synthesis was completed in approximately 30 min using iodomethane as the 11C precursor. The synthesis, purification, characterization, and determination of specific activity are presented and discussed.
卡芬太尼是一种强效阿片受体激动剂，用11C进行标记，以便使用正电子发射断层扫描进行体内研究。该合成反应以碘甲烷作为11C前体，在约30分钟内完成。本文介绍并讨论了该合成、纯化、表征及比活度的测定。
