Chrzanowska-Grenda Beata, Oziębło-Kupczyk 1 Monika, Szumiński Michał, Grenda Marek, Bakunowicz-Łazarczyk Alina
Klin Oczna. 2016;118(2):109-13.
To evaluate morphobiometric properties of the macula (its structure and thickness) in children with a known history of retinopathy of prematurity using optical coherence tomography (SLO/OCT Spectralis).
16 subjects (group B1) (mean age 9.2 years) with a history of stage 3 retinopathy of prematurity treated with retinal laser photocoagulation and 18 subjects (group B2) with a history of spontaneously regressing retinopathy of prematurity (mean age 10.2 years) were studied prospectively. The control group consisted of 21 healthy subjects (group K) (mean age 10.9 years). Each participant underwent a thorough ocular examination and had an optical coherence tomography performed. The U Mann-Whitney and Spearman’s rank correlation tests were used for statistical analyses.
The minimum central foveal thickness and total macular volume were significantly higher in both study groups (B1 and B2) as compared to the control group (K). The subfoveal choroidal thickness was reduced in both study groups (B1 and B2), as compared to the control group (K).
The altered macular structure in eyes with the history of retinopathy of prematurity is related to the presence of all retinal layers within the fovea. However, these changes do not significantly affect visual acuity.
使用光学相干断层扫描(SLO/OCT Spectralis)评估有早产儿视网膜病变病史的儿童黄斑区的形态生物测量特性(其结构和厚度)。
前瞻性研究了16名有3期早产儿视网膜病变病史且接受视网膜激光光凝治疗的受试者(B1组)(平均年龄9.2岁)和18名有早产儿视网膜病变自发消退病史的受试者(B2组)(平均年龄10.2岁)。对照组由21名健康受试者(K组)(平均年龄10.9岁)组成。每位参与者均接受了全面的眼部检查并进行了光学相干断层扫描。采用U曼-惠特尼检验和斯皮尔曼等级相关检验进行统计分析。
与对照组(K组)相比,两个研究组(B1组和B2组)的中央凹最小厚度和黄斑总体积均显著更高。与对照组(K组)相比,两个研究组(B1组和B2组)的黄斑下脉络膜厚度均降低。
有早产儿视网膜病变病史的眼睛中黄斑结构的改变与中央凹内所有视网膜层的存在有关。然而,这些变化并未显著影响视力。