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1
Immortalization of human lymphocytes by co-cultivation with lethally irradiated autologous T-cell lines harbouring human T-cell leukaemia virus-I.通过与携带人类T细胞白血病病毒-I的经致死剂量照射的自体T细胞系共培养使人类淋巴细胞永生化。
J Cancer Res Clin Oncol. 1985;110(1):82-4. doi: 10.1007/BF00402508.
2
Frequent lack of antibodies against human T-cell leukemia virus type I gag proteins p24 or p19 in sera of patients with adult T-cell leukemia.成人T细胞白血病患者血清中经常缺乏针对人类T细胞白血病病毒I型gag蛋白p24或p19的抗体。
J Cancer Res Clin Oncol. 1989;115(3):279-84. doi: 10.1007/BF00391703.
3
Analysis of T cell receptor V beta expression in rabbit T lymphocytes induced to proliferate by an HTLV-I-transformed leukemogenic T cell line.对由人嗜T淋巴细胞病毒I型（HTLV-I）转化的致白血病T细胞系诱导增殖的兔T淋巴细胞中T细胞受体Vβ表达的分析。
J Cancer Res Clin Oncol. 1996;122(8):458-64. doi: 10.1007/BF01187157.
4
Transformation of human fetal thymus and spleen lymphocytes by human T-cell leukemia virus type I.人T细胞白血病病毒I型对人胎儿胸腺和脾脏淋巴细胞的转化作用
Acta Med Okayama. 1985 Apr;39(2):155-9. doi: 10.18926/AMO/31513.
5
Human T Cell Lymphotropic Virus Type 1 Global Prevalence Associated with the Human Development Index: Systematic Review with Meta-Analysis.1型人类嗜T细胞病毒全球流行率与人类发展指数的关联：系统评价与荟萃分析
AIDS Res Hum Retroviruses. 2023 Apr;39(4):145-165. doi: 10.1089/AID.2021.0230. Epub 2023 Feb 15.
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Immunosuppressive T-cell antibody induction for heart transplant recipients.心脏移植受者的免疫抑制性T细胞抗体诱导治疗
Cochrane Database Syst Rev. 2013 Dec 2;2013(12):CD008842. doi: 10.1002/14651858.CD008842.pub2.
7
Co-expression of CD4 and CD8 associated with elevated interleukin-4 in a cord T cell line derived by co-cultivating normal cord leukocytes and an HTLV-II-producing simian leukocyte cell line (Si-IIA).通过将正常脐带白细胞与产生HTLV-II的猿白细胞细胞系（Si-IIA）共培养获得的脐带T细胞系中，CD4和CD8的共表达与白细胞介素-4水平升高相关。
J Cancer Res Clin Oncol. 1993;119(3):137-41. doi: 10.1007/BF01229527.
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A fine balancer: commemorating 40 years of the 's revival.一位出色的平衡者：纪念“[具体事物]”复兴40周年。 （你提供的原文中“the 's revival”这里的's指代不明，所以翻译可能不太准确，需根据完整准确的原文来进一步完善）
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FSH replaced by low-dose hCG in the late follicular phase versus continued FSH for assisted reproductive techniques.在辅助生殖技术中，卵泡晚期用低剂量人绒毛膜促性腺激素替代促卵泡激素与持续使用促卵泡激素的比较。
Cochrane Database Syst Rev. 2013 Mar 28;2013(3):CD010042. doi: 10.1002/14651858.CD010042.pub2.
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Nicotine receptor partial agonists for smoking cessation.尼古丁受体部分激动剂用于戒烟。
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引用本文的文献

1
Depression of early phase of HTLV-I infection in vitro mediated by human beta-interferon.人β-干扰素介导的HTLV-I感染早期阶段的体外抑制
Br J Cancer. 1988 May;57(5):481-8. doi: 10.1038/bjc.1988.111.
2
Selection of HTLV-I positive clones is prevented by prostaglandin A in infected cord blood cultures.在受感染的脐血培养物中，前列腺素A可阻止HTLV-I阳性克隆的选择。
Br J Cancer. 1990 Feb;61(2):207-14. doi: 10.1038/bjc.1990.38.

本文引用的文献

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Establishment and cytological characteristics of two in vitro T-cell lines derived from a child with acute lymphatic leukemia and a man with adult T-cell leukemia in Japan.源自日本一名急性淋巴细胞白血病儿童和一名成人T细胞白血病男性的两株体外T细胞系的建立及其细胞学特征
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Transformation of human leukocytes by cocultivation with an adult T cell leukemia virus producer cell line.通过与成人T细胞白血病病毒产生细胞系共培养实现人白细胞的转化。
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Isolation and characterization of retrovirus from cell lines of human adult T-cell leukemia and its implication in the disease.从成人T细胞白血病细胞系中分离和鉴定逆转录病毒及其在该疾病中的意义。
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A novel T-cell line derived from adult T-cell leukemia.一种源自成人T细胞白血病的新型T细胞系。
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Cell lines producing human T-cell lymphoma virus show altered HLA expression.产生人类T细胞淋巴瘤病毒的细胞系显示出HLA表达改变。
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Infectivity dissociated from transforming activity in a human retrovirus, adult T-cell leukemia virus.
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Detection of H-2Dd and H-2Kd molecules in purified Rauscher leukemia virus.在纯化的劳氏肉瘤病毒中检测H-2Dd和H-2Kd分子。
Int J Cancer. 1983 Mar 15;31(3):329-35. doi: 10.1002/ijc.2910310313.
8
HTLV type I (U. S. isolate) and ATLV (Japanese isolate) are the same species of human retrovirus.I型人类嗜T淋巴细胞病毒（美国分离株）和猿T淋巴细胞白血病病毒（日本分离株）是同一类人类逆转录病毒。
Virology. 1984 Feb;133(1):238-41. doi: 10.1016/0042-6822(84)90446-x.
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Transformation of different phenotypic types of human bone marrow T-lymphocytes by HTLV-1.
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Productive infection and cell-free transmission of human T-cell leukemia virus in a nonlymphoid cell line.人类T细胞白血病病毒在非淋巴细胞系中的增殖性感染及无细胞传播
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通过与携带人类T细胞白血病病毒-I的经致死剂量照射的自体T细胞系共培养使人类淋巴细胞永生化。

Immortalization of human lymphocytes by co-cultivation with lethally irradiated autologous T-cell lines harbouring human T-cell leukaemia virus-I.

作者信息

Akagi T, Ohtsuki Y, Takahashi K, Takeda I, Oka T, Miyoshi I

出版信息

J Cancer Res Clin Oncol. 1985;110(1):82-4. doi: 10.1007/BF00402508.

DOI:10.1007/BF00402508
PMID:2991296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12252570/
Abstract

Human adult peripheral blood lymphocytes were successfully immortalized by co-cultivation with irradiated autologous and homologous T-cell lines harbouring human T-cell leukaemia virus-I (HTLV-I). The efficiency of transformation was the same in both cases. The participation of alloantigen stimulation in co-cultivation procedures is discussed, and it is stressed that factors other than alloantigen stimulation might be required for the efficient immortalization of human T-lymphocytes in vitro by HTLV.

摘要

通过与携带人类T细胞白血病病毒-I（HTLV-I）的经辐照的自体和同源T细胞系共培养，成功使成人外周血淋巴细胞永生化。两种情况下的转化效率相同。讨论了同种异体抗原刺激在共培养过程中的参与情况，并强调在体外通过HTLV高效使人类T淋巴细胞永生化可能需要同种异体抗原刺激以外的因素。