Department of Obstetrics, Gynecology and Reproductive Sciences of the University of Pittsburgh, Division of Urogynecology and Pelvic Reconstructive Surgery, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA.
University of Pittsburgh School of Medicine, Pittsburgh, PA.
Am J Obstet Gynecol. 2018 Nov;219(5):495.e1-495.e10. doi: 10.1016/j.ajog.2018.06.009. Epub 2018 Jun 18.
Enhanced recovery after surgery protocols were developed for colorectal surgery to hasten postoperative recovery. Variations of the protocol are being adopted for gynecological procedures despite limited population and procedure-specific outcome data. Our objective was to evaluate whether implementation of an enhanced recovery after surgery pathway would facilitate reduced length of admission in a urogynecology population.
In this retrospective analysis of patients undergoing pelvic floor reconstructive surgery by 7 female pelvic medicine and reconstructive surgeons, we compared same-day discharge, length of admission and postoperative complications before and after implementation of an enhanced recovery after surgery pathway at a tertiary care hospital. Groups were compared using χ and Student t tests. Candidate variables that could have an impact on patient outcomes with P < .2 were included in multivariable logistic regression models. Satisfaction with surgical experience was assessed using a phone-administered questionnaire the day after discharge.
Mean age and body mass index of 258 women (137 before enhanced recovery after surgery and 121 enhanced recovery after surgery) were 65.5 ± 11.3 years and 28.2 ± 5.0 kg/m. The most common diagnosis was pelvic organ prolapse (n = 242, 93.8%) including stage III pelvic organ prolapse (n = 61, 65.1%). Apical suspension procedures included 58 transvaginal (25.1%), 112 laparoscopic/robotic (48.8%), and 61 obliterative (26.4%). Hysterectomy was performed in 57.4% of women. Demographic and surgical procedures were similar in both groups. Compared with before enhanced recovery after surgery, the enhanced recovery after surgery group had a higher proportion of same-day discharge (25.9% vs 91.7%, P < .001) and a 13.8 hour shorter duration of stay (25.9 ± 13.5 vs 12.1 ± 11.2 hours, P <.001). Operative and postsurgical recovery room times were similar (2.6 ± 0.8 vs 2.6 ± 0.9 hours, P =.955; 3.7 ± 2.1 vs 3.6 ± 2.2 hours, P = .879). Women in the enhanced recovery after surgery group were more likely to be discharged using a urethral catheter (57.9% enhanced recovery after surgery vs 25.4% before enhanced recovery after surgery, P = .005). There were no group differences in total 30 day postoperative complications overall and for the following categories: urinary tract infections, emergency room visits, unanticipated office visits, and return to the operating room. However, enhanced recovery after surgery patients had higher 30 day hospital readmission rates (n = 8, 6.7% vs n = 2, 1.5%, P = .048). Patients before enhanced recovery after surgery were readmitted for myocardial infarction and chest pain. Enhanced recovery after surgery patients were admitted for weakness, chest pain, hyponatremia, wound complications, nausea/ileus, and ureteral obstruction. Three enhanced recovery after surgery patients returned to the operating room for ureteral obstruction (n = 1), incisional hernia (n = 1), and vaginal cuff bleeding (n = 1). Enhanced recovery after surgery patients also had more postoperative nursing phone notes (2.6 ± 1.7 vs 2.1 ± 1.4, P = .030). On multivariable logistic regressions adjusting for age and operative time, same-day discharge was more likely in the enhanced recovery after surgery group (odds ratio, 32.73, 95% confidence interval [15.23-70.12]), while the odds of postoperative complications and emergency room visits were no different. After adjusting for age, operative time, and type of prolapse surgery, readmission was more likely in the enhanced recovery after surgery group (odds ratio, 32.5, 95% confidence interval [1.1-28.1]). In the enhanced recovery after surgery group, patient satisfaction (n = 77 of 121) was reported as very good or excellent by 86.7% for pain control, 89.6% for surgery preparedness, and 93.5% for overall surgical experience; 89.6% did not recall any postoperative nausea during recovery.
Enhanced recovery after surgery implementation in a urogynecology population resulted in a greater proportion of same-day discharge and high patient satisfaction but with slightly increased hospital readmissions within 30 days.
为了加速术后恢复,制定了结直肠手术后的加速康复方案。尽管针对妇科手术的方案具有有限的人群和特定程序的结果数据,但仍在采用该方案的变体。我们的目的是评估在尿失禁患者中实施增强型术后康复方案是否有助于缩短住院时间。
在这项由 7 名女性盆腔医学和重建外科医生对接受盆底重建手术的患者进行的回顾性分析中,我们比较了在一家三级护理医院实施增强型术后康复方案前后的当天出院、住院时间和术后并发症。使用 χ 2 和学生 t 检验比较组间差异。纳入多变量逻辑回归模型的候选变量是那些可能对患者结局产生影响且 P <.2 的变量。术后恢复期间使用电话进行的问卷调查评估了患者对手术体验的满意度。
258 名女性(增强型术后康复前组 137 名,增强型术后康复后组 121 名)的平均年龄和体重指数分别为 65.5 ± 11.3 岁和 28.2 ± 5.0 kg/m 2 。最常见的诊断是盆腔器官脱垂(n = 242,93.8%),包括 III 期盆腔器官脱垂(n = 61,65.1%)。顶端悬吊术包括 58 例经阴道(25.1%)、112 例腹腔镜/机器人(48.8%)和 61 例闭塞性(26.4%)。57.4%的女性接受了子宫切除术。两组的人口统计学和手术程序相似。与增强型术后康复前组相比,增强型术后康复后组当天出院的比例更高(25.9%比 91.7%,P <.001),住院时间缩短 13.8 小时(25.9 ± 13.5 比 12.1 ± 11.2 小时,P <.001)。手术和恢复室时间相似(2.6 ± 0.8 比 2.6 ± 0.9 小时,P.955;3.7 ± 2.1 比 3.6 ± 2.2 小时,P.879)。增强型术后康复后组的女性更有可能通过尿道导管出院(57.9%增强型术后康复后组比 25.4%增强型术后康复前组,P.005)。两组在总体和以下类别中 30 天术后并发症的发生率无差异:尿路感染、急诊就诊、意外门诊就诊和重返手术室。然而,增强型术后康复后组的 30 天住院再入院率较高(n = 8,6.7%比 n = 2,1.5%,P.048)。增强型术后康复前组的患者因心肌梗死和胸痛而再次入院。增强型术后康复后组的患者因虚弱、胸痛、低钠血症、伤口并发症、恶心/肠梗阻和输尿管梗阻而入院。3 名增强型术后康复后组的患者因输尿管梗阻(n = 1)、切口疝(n = 1)和阴道袖口出血(n = 1)返回手术室。增强型术后康复后组的患者术后护理电话记录也更多(2.6 ± 1.7 比 2.1 ± 1.4,P.030)。在调整年龄和手术时间的多变量逻辑回归中,增强型术后康复后组当天出院的可能性更大(优势比,32.73,95%置信区间[15.23-70.12]),而术后并发症和急诊就诊的可能性没有差异。在调整年龄、手术时间和脱垂手术类型后,增强型术后康复后组的再入院率更高(优势比,32.5,95%置信区间[1.1-28.1])。在增强型术后康复后组中,77 名患者(121 名中的 77 名)报告疼痛控制非常好或极好的比例为 86.7%,手术准备非常好或极好的比例为 89.6%,整体手术体验非常好或极好的比例为 93.5%;89.6%的患者在恢复期间没有术后恶心的记忆。
在尿失禁患者中实施增强型术后康复方案可导致更高比例的当天出院和高患者满意度,但 30 天内的住院再入院率略有增加。