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45 岁及以下患者的金属对金属髋关节表面置换术:至少 5 年的随访结果。

Metal on Metal Hip Resurfacing in Patients 45 Years of Age and Younger at Minimum 5-Year Follow-Up.

机构信息

Division of Orthopaedic Surgery, University of Ottawa Faculty of Medicine, The Ottawa Hospital, General Campus, Ottawa, ON, Canada.

出版信息

J Arthroplasty. 2018 Oct;33(10):3196-3200. doi: 10.1016/j.arth.2018.05.041. Epub 2018 Jun 1.

DOI:10.1016/j.arth.2018.05.041
PMID:29914818
Abstract

BACKGROUND

Metal on metal hip resurfacing (MoM-HR) is an alternative to total hip arthroplasty in young and active patients. The purpose was to determine the survivorship of MoM-HR procedures performed in patients aged 45 years and younger assessing patient-reported outcome measures (PROMs) at minimum 5-year follow-up.

METHODS

All 217 patients equal to or younger than 45 years of age at the time of surgical intervention presenting to our center with MoM-HR between May 2002 and May 2011 were prospectively followed. Baseline demographic data, preoperative and postoperative radiographic measurements, and validated PROMs were obtained (Hip Disability and Osteoarthritis Outcome Score, Western Ontario and McMaster Universities Osteoarthritis Index, and University of California, Los Angeles Activity Score). Survivorship was calculated using Kaplan-Meier analysis, and risk factors for failure were identified using multivariate regression analysis.

RESULTS

The overall survivorship excluding septic failures was 94.6% and 93.8% at 5 and 10 years, respectively. Aseptic loosening of the acetabular component was the most common mode of failure (11/20 cases). Gender, head size, and acetabular abduction angle had no significant effect on survivorship. Significant improvements in PROMs were seen for Hip Disability and Osteoarthritis Outcome Score, Western Ontario and McMaster Universities Osteoarthritis Index, and University of California, Los Angeles Activity Scale (P < .001).

CONCLUSION

This study indicates that MoM-HR is a suitable option for young individuals, as demonstrated through improved functional scores and low revision rates. The survivorship of HR in the younger than 45 age-group was similar to that of total hip arthroplasty, as well as HR in older patients. Given the proposed benefits of HR, this procedure may be viewed as a viable option in patients aged younger than 45 years.

摘要

背景

金属对金属髋关节表面置换术(MoM-HR)是年轻且活跃的患者进行全髋关节置换术的替代方法。本研究的目的是确定在 45 岁及以下患者中进行 MoM-HR 手术的生存率,并评估患者报告的结果测量指标(PROMs)在至少 5 年的随访中的表现。

方法

所有在 2002 年 5 月至 2011 年 5 月期间因 MoM-HR 来到本中心就诊且年龄等于或小于 45 岁的 217 例患者都进行了前瞻性随访。获取了基线人口统计学数据、术前和术后影像学测量结果以及经过验证的 PROMs(髋关节残疾和骨关节炎结果评分、西安大略和麦克马斯特大学骨关节炎指数以及加利福尼亚大学洛杉矶活动评分)。使用 Kaplan-Meier 分析计算生存率,并使用多变量回归分析确定失败的风险因素。

结果

在排除感染性失败的情况下,总体生存率分别为 5 年时的 94.6%和 10 年时的 93.8%。髋臼部件的无菌性松动是最常见的失效模式(11/20 例)。性别、股骨头尺寸和髋臼外展角对生存率没有显著影响。髋关节残疾和骨关节炎结果评分、西安大略和麦克马斯特大学骨关节炎指数以及加利福尼亚大学洛杉矶活动评分都有显著改善(P<.001)。

结论

这项研究表明,MoM-HR 是年轻患者的一种合适选择,这从功能评分的提高和低翻修率中得到了证实。在 45 岁以下年龄组中,HR 的生存率与全髋关节置换术以及老年患者的 HR 相似。鉴于 HR 的预期益处,这种手术可能被视为 45 岁以下患者的可行选择。

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