Kho Mark R, Abelardo Agustina D
Department of Surgery, University of the Philippines Manila, Manila, Philippines.
Department of Surgery, Manila Doctors Hospital, Manila, Philippines.
BMJ Case Rep. 2018 Jun 17;2018:bcr-2018-224420. doi: 10.1136/bcr-2018-224420.
We present a rare and interesting case of a 35-year-old woman who initially underwent an uneventful wide excision for a 13 cm left benign phyllodes tumour. She then noted a slowly growing left thyroid nodule 8 months postsurgery which on thyroidectomy 4 years later was shown to be a 6.9cm isolated thyroid metastasis from the phyllodes tumour. As this may be the first reported such case in the literature, implications on histological classification, predictive factors for disease progression, mechanisms of metastasis, and evaluation, management and surveillance of benign phyllodes tumours and thyroid nodule/s with a history of phyllodes tumour can thus be significantly impacted.
我们报告了一例罕见且有趣的病例，一名35岁女性最初因左侧一个13厘米的良性叶状肿瘤接受了顺利的广泛切除手术。术后8个月，她发现左侧甲状腺结节缓慢增大，4年后甲状腺切除显示该结节是叶状肿瘤的一个6.9厘米孤立性甲状腺转移灶。由于这可能是文献中首次报道的此类病例，因此对组织学分类、疾病进展的预测因素、转移机制以及良性叶状肿瘤和有叶状肿瘤病史的甲状腺结节的评估、管理和监测可能会产生重大影响。
