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脊髓痛风导致可逆性四肢瘫:一例报告及文献综述

Spinal gout causing reversible quadriparesis: a case report and literature review.

作者信息

Kaler Jaspreet, Mukhtar Osama, Khalid Mazin, Thapa Shivani, Kaler Ravinder, Ting Brandon, Gayam Vijay

机构信息

Department of Medicine, Interfaith Medical Center, Brooklyn, USA.

Caribbean Medical University, Curacao, Curacao.

出版信息

J Community Hosp Intern Med Perspect. 2018 Jun 12;8(3):111-114. doi: 10.1080/20009666.2018.1472515. eCollection 2018.

Abstract

Gout commonly affects peripheral joints and is rarely found in axial joints, such as the spine and sacroiliac joints. We report a case of a patient that presented with quadriparesis who was empirically treated for spinal gout and a review of relevant literature. A 77-year-old male presented with new-onset quadriparesis that developed over 3 days. MRI imaging was suggestive of tophaceous gout of the cervical spine, but our patient refused a spinal biopsy. He was empirically treated with high-dose steroids and his upper and lower extremities weakness started improving within 3 days and resolved completely. Although spinal gout is uncommon, this case indirectly suggests that gout should be kept as a differential diagnosis when faced with back pain or quadriparesis. This case implies that empiric treatment should be considered when radiographic evidence is suggestive of tophaceous gout of the spine.

摘要

痛风通常累及外周关节,很少见于脊柱和骶髂关节等中轴关节。我们报告一例表现为四肢瘫痪的患者,该患者接受了脊柱痛风的经验性治疗,并对相关文献进行了综述。一名77岁男性出现新发四肢瘫痪,症状在3天内逐渐发展。MRI成像提示颈椎有痛风石性痛风,但我们的患者拒绝进行脊柱活检。他接受了大剂量类固醇的经验性治疗,其上下肢无力在3天内开始改善并完全消失。虽然脊柱痛风并不常见,但该病例间接表明,当面对背痛或四肢瘫痪时,应将痛风作为鉴别诊断之一。该病例提示,当影像学证据提示脊柱有痛风石性痛风时,应考虑经验性治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ee1/5998288/efcbf50809f7/ZJCH_A_1472515_F0001_OC.jpg

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