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腰椎痛风石性痛风酷似脊膜瘤。

Tophaceous gout of the lumbar spine mimicking a spinal meningioma.

作者信息

Ribeiro da Cunha Pedro, Peliz António Judice, Barbosa Marcos

机构信息

Neurosurgery Department, Coimbra University Hospital Center, Coimbra, Praceta Prof. Mota Pinto, 3000-075, Coimbra, Portugal.

出版信息

Eur Spine J. 2018 Apr;27(4):815-819. doi: 10.1007/s00586-016-4831-7. Epub 2016 Nov 5.

DOI:10.1007/s00586-016-4831-7
PMID:27817138
Abstract

PURPOSE

Although gout is a common metabolic disorder, it usually affects distal joints of the appendicular skeleton. Axial spine involvement is rare, with only 131 cases reported in the literature. The authors report a rare case of lumbar spinal gout mimicking a spinal meningioma.

METHODS

A 77-year-old man with a history of gout presented with chronic low back pain and progressive paraparesis. Imaging revealed a lumbar spine compressive mass lesion with a dural tail signal. The differential diagnosis was thought to be straightforward favoring a spinal meningioma. Tophaceous gout was never considered. The presence of a dural tail associated with the lesion is an interesting detail of this case, that strongly misguided it and to the best of our knowledge it is the first one reported in the literature.

RESULTS

The patient underwent surgery and intra-operative findings were surprisingly different from those expected, revealing a chalky white mass lesion firmly adherent and compressing the dural sac. It was completely excised, leaving the dura intact. Histopathology confirmed the diagnosis of tophaceous gout. The patient was sent to physical therapy and had a complete remission of pain and neurological deficit, regaining his walking capacity.

CONCLUSION

Although spinal gout is rare, it should be considered in the differential diagnosis for patients presenting with symptoms of spinal stenosis, a suspicion of neoplastic lesion of the spine, and a previous history of gout. Early diagnosis can ensure proper and timely medical management, perhaps avoiding neurological compromise and the need for surgery.

摘要

目的

尽管痛风是一种常见的代谢紊乱疾病,但通常影响四肢骨骼的远端关节。脊柱受累罕见,文献中仅报道了131例。作者报告了一例罕见的腰椎痛风病例,其表现类似脊膜瘤。

方法

一名有痛风病史的77岁男性,出现慢性腰痛和进行性下肢轻瘫。影像学检查显示腰椎有一个压迫性肿块病变,伴有硬脊膜尾征信号。鉴别诊断被认为很简单,倾向于脊膜瘤。从未考虑过痛风石性痛风。与病变相关的硬脊膜尾征的存在是该病例一个有趣的细节,这严重误导了诊断,据我们所知,这是文献中首次报道。

结果

患者接受了手术,术中发现令人惊讶地与预期不同,显示出一个灰白色肿块病变,牢固地附着并压迫硬脊膜囊。将其完全切除,硬脊膜保持完整。组织病理学证实为痛风石性痛风。患者接受了物理治疗,疼痛和神经功能缺损完全缓解,恢复了行走能力。

结论

尽管脊柱痛风罕见,但对于出现脊柱狭窄症状、怀疑有脊柱肿瘤性病变且有痛风病史的患者,在鉴别诊断中应考虑到。早期诊断可确保适当及时的医疗管理,或许能避免神经功能损害和手术需求。

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Gout in the Spine: Imaging, Diagnosis, and Outcomes.脊柱痛风:影像学、诊断及预后
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Clinical utility of dual-energy CT for gout diagnosis.双能CT在痛风诊断中的临床应用价值
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