Zafeiris T, Gothner M, Hempel Overhage C, Heil G, Roetman B
Klinik für Unfallchirurgie und Orthopädie, Klinikum Maria Hilf GmbH, Sandradstraße 43, 41061, Mönchengladbach, Deutschland.
Klinik für Unfallchirurgie und Orthopädie, Klinikum Rheine, Mathias-Spital Rheine, Frankenburgstraße 31, 48431, Rheine, Deutschland.
Unfallchirurg. 2018 Nov;121(11):930-934. doi: 10.1007/s00113-018-0517-4.
Chronic lymphatic leukaemia (CLL) is one of the most common leukaemic diseases in middle Europe. Pathological fractures are rare findings in patients with CLL. The diagnosis of CLL is in most cases an incidental finding as it often stays asymptomatic for years. This article presents an interesting case of a 65-year-old male patient with known asymptomatic CLL for 5 years and fractures of the proximal femur and proximal radius after trauma. During the hospital stay the patient suffered multiple pathological fractures with histological findings of bony infiltration of the CLL and an acute phase, which was treated by combination chemotherapy.
慢性淋巴细胞白血病（CLL）是中欧最常见的白血病之一。病理性骨折在CLL患者中是罕见的表现。CLL的诊断在大多数情况下是偶然发现的，因为它通常多年无症状。本文介绍了一例有趣的病例，一名65岁男性患者，已知无症状CLL 5年，外伤后出现股骨近端和桡骨近端骨折。住院期间，患者发生多处病理性骨折，组织学检查发现CLL骨浸润处于急性期，采用联合化疗进行治疗。
