National Laboratory of Pattern Recognition, Institute of Automation, The Chinese Academy of Sciences, Beijing, 100190, China.
Brainnetome Center, Institute of Automation, The Chinese Academy of Sciences, Beijing, 100190, China.
Neurosci Bull. 2018 Aug;34(4):592-604. doi: 10.1007/s12264-018-0243-5. Epub 2018 Jun 18.
Neuroimaging has opened new opportunities to study the neural correlates of consciousness, and provided additional information concerning diagnosis, prognosis, and therapeutic interventions in patients with disorders of consciousness. Here, we aim to review neuroimaging studies in chronic disorders of consciousness from the viewpoint of the brain network, focusing on positron emission tomography, functional MRI, functional near-infrared spectroscopy, electrophysiology, and diffusion MRI. To accelerate basic research on disorders of consciousness and provide a panoramic view of unconsciousness, we propose that it is urgent to integrate different techniques at various spatiotemporal scales, and to merge fragmented findings into a uniform "Brainnetome" (Brain-net-ome) research framework.
神经影像学为研究意识的神经相关性开辟了新的机会，并为意识障碍患者的诊断、预后和治疗干预提供了更多信息。在这里，我们旨在从脑网络的角度回顾慢性意识障碍的神经影像学研究，重点关注正电子发射断层扫描、功能磁共振成像、功能近红外光谱、电生理学和弥散磁共振成像。为了加速意识障碍的基础研究，并提供无意识的全景图，我们建议迫切需要在不同的时空尺度上整合不同的技术，并将碎片化的发现合并到一个统一的“脑网络组”（Brain-net-ome）研究框架中。
