Obstructive uropathy, renal dysplasia and nodular renal blastema: is there a relationship to Wilms tumor?

We report 3 cases of renal dysplasia related to congenital obstructive uropathy and associated with nodular renal blastema. The literature is reviewed in regard to this relationship, as well as the relationship of nodular renal blastema with Wilms tumor and Wilms tumor with congenital genitourinary anomalies. The possible implication of nodular renal blastema associated with dysplasia and obstructive uropathy is emphasized with respect to the risk of neoplastic change.