Holy Cross Orthopedic Institute, 5597 North Dixie Highway, Fort Lauderdale, FL, USA.
Department of Orthopaedic Surgery, Cleveland Clinic, 9500 Euclid Avenue/A40, Cleveland, OH, 44195, USA.
J Racial Ethn Health Disparities. 2019 Feb;6(1):101-109. doi: 10.1007/s40615-018-0504-z. Epub 2018 Jun 18.
There is a relative paucity of studies that characterized racial disparities in revision total knee arthroplasty (TKA). Therefore, this study was specifically conducted to evaluate the following: (1) incidence; (2) annual burden; (3) causes; and (4) age group distribution of revision TKA among different racial groups in the US sample population.
The PearlDiver database was utilized to identify patients with knee osteoarthritis (OA) who underwent primary then subsequent revision TKA from January 2007 to December 2014. Patients were stratified by race, and subset stratification by age was also performed. In each racial cohort, the overall incidence of revision TKA, annual revision burdens, and causes of revisions were calculated and compared. Additionally, a sub-analysis for the incidence of revision TKA stratified by age, in each cohort, was performed. Statistical analysis was performed to demonstrate revision incidence, burden, causes, and age distribution.
Revision incidence and burden were the highest in the African-American cohort (12.4%, 11.1%), (p < 0.001) and was lowest in the Asian cohort (3.4%, 3.3%) (p < 0.001). Across all cohorts, mechanical complications of the joint prosthesis were the most common cause of revision followed by periprosthetic joint infection, while contracture was the least common (p < 0.001). Subset analysis by age revealed that the highest incidence of revision TKA was in patients less than 40 years old in the Caucasian cohort (27.1%). The African-American (17.8%), other races (7.9%), and Hispanic (16.5%) cohorts had the highest incidence of revision in the 40 to 64 years age range. Among the Asian (4.1%) and Native American (9.7%) cohorts, revision incidence was highest in patients older than 65 years.
The present study demonstrated that racial disparities, highlighted by previous studies mainly in primary TKA, extend to influence revision TKA. Among the studied racial cohorts, race may affect outcomes and our results will help expand the current literature particularly on its role in revision TKA.
在研究翻修全膝关节置换术(TKA)中的种族差异方面,相关研究相对较少。因此,本研究专门评估了以下方面:(1)发生率;(2)年负担;(3)原因;以及(4)美国样本人群中不同种族群体的翻修 TKA 的年龄组分布。
利用 PearlDiver 数据库,确定了 2007 年 1 月至 2014 年 12 月间患有膝骨关节炎(OA)并接受初次翻修 TKA 的患者。根据种族对患者进行分层,并按年龄进行亚组分层。在每个种族队列中,计算并比较了翻修 TKA 的总体发生率、年翻修负担以及翻修原因。此外,还对每个队列中按年龄分层的翻修 TKA 的发生率进行了亚分析。通过统计学分析来展示翻修的发生率、负担、原因和年龄分布。
非裔美国人队列的翻修发生率和负担最高(12.4%,11.1%)(p<0.001),而亚裔队列的发生率和负担最低(3.4%,3.3%)(p<0.001)。在所有队列中,关节假体的机械并发症是最常见的翻修原因,其次是假体周围关节感染,而挛缩是最不常见的原因(p<0.001)。按年龄进行的亚组分析显示,在白人队列中,40 岁以下患者的翻修 TKA 发生率最高(27.1%)。非裔美国人(17.8%)、其他种族(7.9%)和西班牙裔(16.5%)队列中,40 至 64 岁年龄组的翻修发生率最高。在亚洲人(4.1%)和美洲原住民(9.7%)队列中,65 岁以上患者的翻修发生率最高。
本研究表明,种族差异——先前的研究主要集中在初次 TKA 中——延伸至翻修 TKA。在所研究的种族队列中,种族可能会影响结果,我们的研究结果将有助于扩展当前文献,特别是在翻修 TKA 中的作用。