Suyama Y, Iwai M, Fujii H, Miyoshi M
Gan No Rinsho. 1985 May;31(5):518-21.
Alteration in blood coagulation and fibrinolysis were observed serially after TAE 37 times by measuring PT, APTT, FDP, fibrinogen, AT III, plasminogen, and alpha 2-macroglobulin. Immediately after TAE, PT and APTT were prolonged, Fbg AT III, alpha 2-M, and platelets decreased, and FDP increased. These changes within 24 hours suggested that coagulation activities were accelerated, and fibrinolysis followed. Within four weeks after TAE, PT and APTT became most prolonged one to three days after, while AT III, Plg, and alpha 2-M became lowest on the third to seventh days. It is suggested that these decrease were mainly due to suppressed production resulting from damage of the residual liver.
通过测定PT、APTT、FDP、纤维蛋白原、抗凝血酶III（AT III）、纤溶酶原和α2-巨球蛋白，对37例TAE术后患者的血液凝固和纤维蛋白溶解情况进行了连续观察。TAE术后即刻，PT和APTT延长，纤维蛋白原、AT III、α2-M和血小板减少，FDP增加。这些24小时内的变化提示凝血活性加快，随后发生纤维蛋白溶解。TAE术后四周内，PT和APTT在术后1至3天延长至最长，而AT III、纤溶酶原和α2-M在第3至7天降至最低。提示这些降低主要是由于残余肝损伤导致生成受抑制。
