用合成促肾上腺皮质激素4-9类似物治疗阿尔茨海默病。
Treatment of Alzheimer's disease with a synthetic ACTH 4-9 analog.
作者信息
Soininen H, Koskinen T, Helkala E L, Pigache R, Riekkinen P J
出版信息
Neurology. 1985 Sep;35(9):1348-51. doi: 10.1212/wnl.35.9.1348.
PMID:2991817
Abstract
The synthetic ACTH 4-9 analog, Org 2766, was administered to 77 Alzheimer's patients for 6 months in a double-blind, placebo-controlled study. Although Org 2766 was tolerated well, no significant effect of Org 2766 could be demonstrated in terms of rating scales or cognitive functions.
摘要
在一项双盲、安慰剂对照研究中，对77名阿尔茨海默病患者给予合成促肾上腺皮质激素4-9类似物Org 2766，为期6个月。尽管Org 2766耐受性良好，但在评分量表或认知功能方面未显示出Org 2766有显著效果。
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