兔门静脉中对多巴胺敏感的腺苷酸环化酶
Dopamine-sensitive adenylate cyclase in rabbit portal vein.
作者信息
Amenta F
出版信息
Neurosci Lett. 1985 May 23;56(3):279-82. doi: 10.1016/0304-3940(85)90255-1.
PMID:2991823
Abstract
The effect of dopamine (DA) on 3',5'-cyclic adenosine monophosphate (cAMP) generation in the rabbit portal vein was investigated. Dopamine added to homogenates of rabbit portal vein increased the concentration of cAMP. DA-elicited cAMP increase was exclusively inhibited by DA antagonists fluphenazine and haloperidol suggesting the existence of DA receptors (of the DA1 subtype) in the portal vein.
摘要
研究了多巴胺（DA）对兔门静脉中3',5'-环磷酸腺苷（cAMP）生成的影响。向兔门静脉匀浆中添加多巴胺可增加cAMP的浓度。多巴胺引起的cAMP增加完全被多巴胺拮抗剂氟奋乃静和氟哌啶醇抑制，这表明门静脉中存在多巴胺受体（DA1亚型）。
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