Howard D J, Lund V J
Otolaryngol Head Neck Surg. 1985 Jun;93(3):338-41. doi: 10.1177/019459988509300309.
Adenoid cystic carcinoma of the nasal cavity and paranasal sinuses has a unique natural history. It has a propensity for frequent local recurrence and early perineural and hematogenous spread. These factors, together with a complex anatomic situation, make adequate oncologic surgery extremely difficult. The incidence of local recurrence is lower in those patients receiving more radical primary surgery, but the choice between conservative and radical management may not alter prognosis. Indeed, it is doubtful if any patients are cured of this disease.
鼻腔和鼻窦腺样囊性癌具有独特的自然病程。它易于频繁局部复发，并早期出现神经周围和血行播散。这些因素，再加上解剖结构复杂，使得进行充分的肿瘤手术极为困难。接受更根治性初次手术的患者局部复发率较低，但保守治疗和根治性治疗之间的选择可能不会改变预后。实际上，是否有患者能治愈这种疾病令人怀疑。
