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氯吡格雷治疗与神经介入操作的药物遗传学:精准医学需要精准数据。

Pharmacogenetics of Clopidogrel Therapy and Neurointerventional Procedures: We Need Precision Data for Precision Medicine.

机构信息

Institute of Molecular Genetics and Genetic Engineering, University of Belgrade, Belgrade, Serbia.

出版信息

Clin Pharmacol Ther. 2019 Mar;105(3):547-549. doi: 10.1002/cpt.1105. Epub 2018 Jun 19.

Abstract

Genetics has given a real boost to personalized and precision medicine, providing data used either for precise diagnostics, prediction of the course of illness, or for selecting therapy and tailoring it. Pharmacogenetics, as a discipline researching connection between genetic background of an individual and the effect of a certain drug, has created new possibilities in medicine. One of the most researched drugs in pharmacogenetics is certainly clopidogrel.

摘要

遗传学为个性化和精准医学提供了真正的助力,为精准诊断、疾病进程预测,或者治疗选择和定制提供了所使用的数据。药物遗传学作为研究个体遗传背景与特定药物效果之间关系的学科,为医学创造了新的可能性。在药物遗传学中研究最多的药物之一当然是氯吡格雷。

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