Liu Yao, Guo Gai-Li, Wen Bin, Wang Shouzheng, Ou-Yang Wen-Bin, Xie Yongquan, Pan Xiang-Bin
Department of Cardiovascular Surgery, National Center for Cardiovascular Disease, China & Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Echocardiography. 2018 Oct;35(10):1507-1511. doi: 10.1111/echo.14055. Epub 2018 Jun 19.
Percutaneous balloon mitral valvuloplasty (PBMV) is the treatment of choice in patients with isolated mitral stenosis. This study aimed to assess the feasibility of PBMV under echocardiography guidance only of isolated mitral stenosis (MS).
From October 2016 to Dec 2017, 20 consecutive patients with severe MS underwent PBMV with echocardiography as the only imaging modality at a single center. Outpatient follow-up including chest radiography, electrocardiography, and transthoracic echocardiography was conducted at 1, 3,6, and 12 months after the procedure.
All 20 patients successfully underwent PBMV under echocardiography guidance without radiation and contrast agent. Among them, 2 patients were pregnant, 5 had chronic renal failure, and 1 had history of allergy to contrast. Mitral transvalvular pressure gradient measured at catheterization dropped from 13.35 ± 2.85 mm Hg to 5.10 ± 1.17 mm Hg (P < .01). Mitral valve area increased from 0.82 ± 0.10 cm pre-PBMV to 1.88 ± 0.24 cm post-PBMV (P < .01). Mean balloon diameter was 26.63 ± 0.93 mm. Mild mitral regurgitation developed in 6 patients. Mean follow-up duration was 6.27 ± 3.12 months. At last follow-up, mitral valve area remained high (1.71 ± 0.14 cm ) and mean transmitral pressure gradient low (6.07 ± 1.03 mm Hg). No pericardial effusion or peripheral vascular complications occurred.
In this small experience, PBMV could be successfully performed under only echocardiography guidance and appeared safe and effective while avoiding radiation and contrast agent use.
经皮球囊二尖瓣成形术(PBMV)是单纯二尖瓣狭窄患者的首选治疗方法。本研究旨在评估仅在超声心动图引导下进行PBMV治疗单纯二尖瓣狭窄(MS)的可行性。
2016年10月至2017年12月,20例重度MS患者在单一中心仅以超声心动图作为成像方式接受了PBMV。术后1、3、6和12个月进行门诊随访,包括胸部X线摄影、心电图和经胸超声心动图检查。
所有20例患者均在超声心动图引导下成功接受了PBMV,未使用辐射和造影剂。其中,2例患者为孕妇,5例患有慢性肾衰竭,1例有造影剂过敏史。导管检查时测得的二尖瓣跨瓣压差从13.35±2.85 mmHg降至5.10±1.17 mmHg(P<.01)。二尖瓣瓣口面积从PBMV术前的0.82±0.10 cm²增加至术后的1.88±0.24 cm²(P<.01)。平均球囊直径为26.63±0.93 mm。6例患者出现轻度二尖瓣反流。平均随访时间为6.27±3.12个月。在末次随访时,二尖瓣瓣口面积仍较高(1.71±0.14 cm²),平均跨瓣压差较低(6.07±1.03 mmHg)。未发生心包积液或外周血管并发症。
在这一小样本经验中,仅在超声心动图引导下即可成功进行PBMV,且在避免使用辐射和造影剂的情况下显得安全有效。