对与睾酮补充相关的在线内容进行分析。
An analysis of online content related to testosterone supplementation.
机构信息
a Faculty of Pharmacy & Pharmaceutical Sciences , University of Alberta , Edmonton , Alberta , Canada.
出版信息
Aging Male. 2019 Jun;22(2):141-149. doi: 10.1080/13685538.2018.1482867. Epub 2018 Jun 20.
OBJECTIVE
To describe the quality of online information on testosterone replacement therapy (TRT) in men.
METHODS
A quantitative content analysis was conducted on websites providing patient-directed information on TRT for the purpose of treating late onset hypogonadism (LOH). Websites were identified through Google in March 2017. The DISCERN instrument was used to determine the quality of health information.
RESULTS
A total of 20 websites met inclusion criteria. Websites were primarily from the United States (45%), United Kingdom (25%), and Australia (15%). Sources of information were cited by 40% of websites. Several websites (40%) claimed that TRT had benefits, with 25% claiming that TRT was effective for treating LOH. TRT was described as a safe therapy by one website (5%), with gynecomastia (35%) and increased hematocrit (35%) representing the most commonly described side effects. Prostate specific antigen (35%) and serum testosterone monitoring (30%) were the most commonly described monitoring parameters. The mean DISCERN score was 46.4, indicating fair quality information. The Flesh-Kincaid Grade Level was 12.2.
CONCLUSION
Online TRT information is incomplete, often failing to describe important safety information and the need for regular monitoring.
目的
描述男性睾酮替代疗法（TRT）的在线信息质量。
方法
通过 2017 年 3 月谷歌搜索，对旨在治疗迟发性性腺功能减退症（LOH）的患者导向 TRT 信息的网站进行了定量内容分析。使用 DISCERN 工具来确定健康信息的质量。
结果
共有 20 个网站符合纳入标准。这些网站主要来自美国（45%）、英国（25%）和澳大利亚（15%）。40%的网站引用了信息来源。一些网站（40%）声称 TRT 有好处，25%声称 TRT 对治疗 LOH 有效。一个网站（5%）将 TRT 描述为一种安全的治疗方法，而最常描述的副作用是男性乳房发育（35%）和血细胞比容升高（35%）。前列腺特异性抗原（35%）和血清睾酮监测（30%）是最常描述的监测参数。DISCERN 平均得分为 46.4，表明信息质量一般。Flesh-Kincaid 阅读水平为 12.2。
结论
在线 TRT 信息不完整，经常未能描述重要的安全信息和定期监测的必要性。
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