Laine Christine M, Laine Tero
Consultant in Endocrinology, Institute of Medicine, Sahlgrenska University Hospital and University of Gothenburg, Gothenburg, Sweden.
Senior Consultant in Paediatric Orthopaedics, Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska University Hospital and University of Gothenburg, Gothenburg, Sweden.
Eur Endocrinol. 2013 Aug;9(2):141-144. doi: 10.17925/EE.2013.09.02.141. Epub 2013 Aug 23.
Osteoporosis is traditionally regarded as a disease of elderly women. However, this bone disorder occurs in patients of both sexes and of all ages and is also increasingly recognised in the paediatric setting. In particular, patients, including young children, with other chronic diseases are at risk of developing bone fragility. There are also several forms of hereditary osteoporosis, which should be identified at an early stage to ensure adequate treatment. The diagnosis of osteoporosis in children is challenging, since their bone mineral density (BMD) is affected by growth and pubertal development. In addition to low BMD, a child must also exhibit a significant proneness to fractures before the osteoporosis diagnosis can be made. Through early diagnosis and treatment for paediatric bone fragility, we can also ameliorate bone health in adulthood. In this article we review the aetiology, known risk factors and the diagnostic criteria of osteoporosis in the young.
传统上,骨质疏松症被视为老年女性的疾病。然而,这种骨病在所有年龄段的男性和女性患者中均有发生,并且在儿科环境中也越来越受到认可。特别是患有其他慢性病的患者,包括幼儿,有发生骨质脆弱的风险。此外,还有几种遗传性骨质疏松症,应尽早识别以确保进行充分治疗。儿童骨质疏松症的诊断具有挑战性,因为他们的骨矿物质密度(BMD)受生长和青春期发育的影响。除了低骨密度外,儿童在做出骨质疏松症诊断之前还必须表现出明显的骨折倾向。通过对儿童骨质脆弱进行早期诊断和治疗,我们还可以改善成年期的骨骼健康。在本文中,我们综述了年轻人骨质疏松症的病因、已知风险因素和诊断标准。