Ferreira F S, Brito S V, Coutinho H D M, Souza E P, Almeida W O, Alves R R N
Universidade Federal do Vale do São Francisco, Colegiado Acadêmico de Ecologia, Senhor do Bonfim, BA, Brazil.
Universidade Federal do Maranhão, Centro de Ciências Agrárias e Ambientais, Chapadinha, MA, Brazil.
Ecohealth. 2018 Sep;15(3):619-626. doi: 10.1007/s10393-018-1345-2. Epub 2018 Jun 19.
In Brazil, although a large number of animals are used in traditional medicine (at least 354 species), information about their biological activities is scarce. In this context, the objective of this study was to evaluate the bactericidal potential of zootherapeutic by-products from animals used in Brazilian traditional medicine and discuss the ecological and cultural consequences of such practices. The species analyzed were: Tupinambis merianae (skin), Iguana iguana (skin and body fat), Crotalus durissus (skin and body fat), Boa constrictor (skin), Euphractus sexcinctus (body fat) and Coendou prehensilis (quills). Experiments were performed with standard clinical strains of Escherichia coli (EC-ATCC10536) and Staphylococcus aureus (SA-ATCC 25923). For the microbiological assay, the zootherapeutics were evaluated using serial microdilutions. The results indicate that none of the samples possess inhibitory activity against standard bacterial strains. The in vitro ineffectiveness of the analyzed products demonstrate a necessity for new pharmacological research that encompass a large number of species of medicinal animals as well as highlight the importance of zootherapy in the context of plans for animal conservation.
在巴西,尽管大量动物被用于传统医学(至少354种),但有关它们生物活性的信息却很匮乏。在此背景下,本研究的目的是评估巴西传统医学中所用动物的动物疗法副产品的杀菌潜力,并讨论此类做法的生态和文化后果。所分析的物种有:阿根廷黑白泰加蜥(皮肤)、绿鬣蜥(皮肤和体脂)、三色矛头蝮(皮肤和体脂)、红尾蚺(皮肤)、六带犰狳(体脂)和南美卷尾豪猪(刺)。实验使用了大肠杆菌(EC - ATCC10536)和金黄色葡萄球菌(SA - ATCC 25923)的标准临床菌株进行。对于微生物学检测,采用系列微量稀释法对动物疗法产品进行评估。结果表明,没有一个样品对标准细菌菌株具有抑制活性。所分析产品在体外无效果表明有必要开展新的药理学研究,涵盖大量药用动物物种,并突出动物疗法在动物保护计划背景下的重要性。