From the Department of Anesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China.
Reg Anesth Pain Med. 2018 Nov;43(8):825-831. doi: 10.1097/AAP.0000000000000822.
It has recently been proposed that an infraclavicular brachial plexus block (BPB) at the costoclavicular (CC) space may overcome some of the limitations of the lateral sagittal (LS) approach. In this study, we hypothesized that the CC approach will produce faster onset of sensory blockade of the 4 major terminal nerves of the brachial plexus than the LS approach.
Forty patients undergoing elective upper extremity surgery under a BPB were randomized to receive either the LS (Gp-LS, n = 20) or CC approach (Gp-CC, n = 20) for infraclavicular BPB. Twenty-five milliliters of 0.5% ropivacaine was used for the BPB in both study groups. Sensory-motor blockade of the ipsilateral median, radial, ulnar, and musculocutaneous nerves was assessed by a blinded observer at regular intervals for 45 minutes after the block. Sensory block was assessed using a verbal rating scale (0-100) and motor block using a 3-point qualitative scale (0-2). Onset of sensory (primary outcome variable) and motor blockade was defined as the time it took to achieve a sensory verbal rating scale of 30 or less and motor grade of 1 or less, respectively. Time to readiness for surgery was defined as the time it took to achieve a sensory score of 30 or less and motor grade of 1 or less in all the 4 nerves tested.
The overall sensory onset time (median [interquartile range]) was significantly faster (P = 0.004) in Gp-CC (10 [10-26.25] minutes) than in Gp-LS (20 [15-30] minutes). The overall sensory score was significantly lower in Gp-CC than in Gp-LS at 5 (P < 0.001), 10 (P = 001), 15 (P = 0.001), and 20 (P = 0.04) minutes after the BPB. The overall motor score was significantly lower (P = 0.009) in Gp-CC than in Gp-LS at 10 minutes after the BPB. There were more (P = 0.04) patients with complete sensory-motor blockade at 20 minutes after the BPB in Gp-CC (25%) than in Gp-LS (0%). Time to readiness for surgery was also significantly faster (P = 0.002) in Gp-CC (10 [10-26.5] minutes) than in Gp-LS (20 [15-30] minutes).
The CC approach for infraclavicular BPB produces faster onset of sensory blockade and earlier readiness for surgery than the LS approach.
This study was registered at the Centre for Clinical Trials of The Chinese University of Hong Kong, identifier CUHK_CCT00389.
最近有人提出,锁骨下臂丛神经阻滞(BPB)在肋锁(CC)间隙可能会克服外侧矢状(LS)入路的一些局限性。在这项研究中,我们假设 CC 入路会比 LS 入路更快地产生臂丛神经 4 大终末神经的感觉阻滞。
40 例行 BPB 的择期上肢手术患者被随机分为 LS(Gp-LS,n = 20)或 CC 组(Gp-CC,n = 20)进行锁骨下 BPB。两组均使用 25ml0.5%罗哌卡因进行 BPB。在阻滞后 45 分钟内,由一名盲法观察者定期评估同侧正中神经、桡神经、尺神经和肌皮神经的感觉-运动阻滞情况。感觉阻滞采用言语评分量表(0-100)评估,运动阻滞采用 3 分定性量表(0-2)评估。感觉阻滞(主要观察变量)和运动阻滞的起始时间定义为达到感觉言语评分 30 或以下和运动分级 1 或以下的时间。手术准备时间定义为所有 4 个测试神经达到感觉评分 30 或以下和运动分级 1 或以下的时间。
Gp-CC 组(10 [10-26.25] 分钟)的总体感觉起始时间(中位数[四分位距])明显快(P = 0.004)于 Gp-LS 组(20 [15-30] 分钟)。Gp-CC 组的总体感觉评分在 BPB 后 5(P < 0.001)、10(P = 0.01)、15(P < 0.001)和 20(P = 0.04)分钟时明显低于 Gp-LS 组。Gp-CC 组的总体运动评分在 BPB 后 10 分钟时明显低于 Gp-LS 组(P = 0.009)。Gp-CC 组在 BPB 后 20 分钟时(25%)感觉运动阻滞完全的患者明显多于 Gp-LS 组(0%)(P = 0.04)。Gp-CC 组的手术准备时间也明显快于 Gp-LS 组(P = 0.002),Gp-CC 组为 10 [10-26.5] 分钟,Gp-LS 组为 20 [15-30] 分钟。
锁骨下 BPB 的 CC 入路比 LS 入路更快地产生感觉阻滞,更早地准备手术。
本研究在中国香港中文大学临床试验中心注册,注册号为 CUHK_CCT00389。