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锁骨上和锁骨下臂丛神经阻滞致同侧膈肌麻痹:一项随机观察者盲法研究。

Ipsilateral hemidiaphragmatic paresis after a supraclavicular and costoclavicular brachial plexus block: A randomised observer blinded study.

机构信息

From the Department of Anesthesiology and Critical Care, Mahatma Gandhi Medical College and Research Institute, Sri Balaji Vidyapeeth, Pillayarkuppam, Pondicherry, India (TS, IM, NK) and Department of Anaesthesia & Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China (MKK).

出版信息

Eur J Anaesthesiol. 2019 Oct;36(10):787-795. doi: 10.1097/EJA.0000000000001069.

Abstract

BACKGROUND

The costoclavicular brachial plexus block (BPB) produces faster onset of sensory motor blockade than the lateral sagittal approach. However, the incidence of phrenic nerve palsy (PNP) after a costoclavicular BPB is not known.

OBJECTIVES

The current study compared the incidence of ipsilateral hemidiaphragmatic paresis, and thus PNP, between a supraclavicular and costoclavicular BPB.

DESIGN

Randomised observer blinded study.

SETTING

Operating room.

PATIENTS

Forty patients undergoing right-sided upper extremity surgery.

INTERVENTION

All patients received either a supraclavicular group or costoclavicular group BPB using 20 ml of an equal mixture of 0.5% bupivacaine and 2% lidocaine with 1 : 200 000 epinephrine.

MAIN OUTCOME MEASURES

Measurements included ipsilateral hemidiaphragmatic excursion and peak expiratory flow rate (PEFR) taken before and at 30 min after the BPB. Diaphragmatic excursion was measured using M-mode ultrasound during normal breathing, deep breathing and with the sniff manoeuvre. Ipsilateral PNP was defined as a reduction in hemidiaphragmatic excursion by at least 50% during deep breathing at 30 min after the BPB.

RESULTS

The incidence of ipsilateral PNP was lower (P = 0.008) in the costoclavicular group (5%) than in the supraclavicular group (45%). Fewer (P = 0.04) patients in the costoclavicular group [1(5%)] exhibited a positive sniff test, with paradoxical movement of the diaphragm, than in the supraclavicular group [7(35%)]. PEFRs were similar (P = 0.09) between the groups. When ipsilateral hemidiaphragmatic paresis was present, the median reduction in PEFR was 32% (interquartile range 23.6 to 45.5%).

CONCLUSION

Costoclavicular BPB produces a lower incidence of ipsilateral PNP than a supraclavicular BPB.

NAME OF REGISTRY

Clinical Trial Registry of India.

IDENTIFIER

CTRI/2017/09/009763.

摘要

背景

与外侧矢状入路相比,锁骨下臂丛阻滞(BPB)可更快地产生感觉运动阻滞。然而,锁骨下 BPB 后膈神经麻痹(PNP)的发生率尚不清楚。

目的

本研究比较了锁骨上和锁骨下 BPB 后同侧膈肌麻痹(即 PNP)的发生率。

设计

随机观察者盲法研究。

设置

手术室。

患者

40 例接受右侧上肢手术的患者。

干预

所有患者均接受锁骨上组或锁骨下组 BPB,使用 20ml 0.5%布比卡因和 2%利多卡因与 1:200000 肾上腺素的等体积混合物。

主要观察指标

测量包括在 BPB 前和 30 分钟后进行的同侧膈肌运动幅度和呼气峰流速(PEFR)。使用 M 模式超声在正常呼吸、深呼吸和嗅探动作期间测量膈肌运动幅度。同侧 PNP 定义为 BPB 后 30 分钟深呼吸时膈肌运动幅度至少降低 50%。

结果

锁骨下组(5%)的同侧 PNP 发生率低于锁骨上组(45%)(P=0.008)。锁骨下组(1 例 [5%])出现阳性嗅探试验(膈肌出现矛盾运动)的患者少于锁骨上组(7 例 [35%])(P=0.04)。两组的 PEFR 相似(P=0.09)。当同侧膈肌麻痹存在时,PEFR 的中位数降低 32%(四分位间距 23.6 至 45.5%)。

结论

与锁骨上 BPB 相比,锁骨下 BPB 可降低同侧 PNP 的发生率。

注册号

印度临床试验注册处。

标识符

CTRI/2017/09/009763。

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