Santos Heloísa Laís Rosario Dos, Barbosa Inessa da Silva, de Oliveira Thaís Feitosa Leitão, Sarmento Viviane Almeida, Trindade Soraya Castro
State University of Feira de Santana, Salvador, Bahia Federal University of Bahia, Salvador, Brazil.
Medicine (Baltimore). 2018 Jun;97(25):e11052. doi: 10.1097/MD.0000000000011052.
Sickle-cell disease (SCD), which involves morphological changes to the red blood cells, is the most common hemoglobinopathy worldwide. This conformational change in erythrocytes affects multiple organs and systems, including the hard and soft tissues of the stomatognathic system. The objective of this study was to provide a description of the maxillomandibular positioning of patients using computed tomography in a case series of 40 patients with SCD. To define the facial profile of patients, 2-dimensional (2D) and 3-dimensional (3D) McNamara and Steiner cephalometric tracings were performed. The results showed that there is a tendency to maxillary protrusion in 2D and 3D analyses. There was no statistical difference between the 2D and 3D evaluations; additionally, sex affected the maxillomandibular positioning of patients, but only in McNamara evaluations.
镰状细胞病(SCD)涉及红细胞的形态变化,是全球最常见的血红蛋白病。红细胞的这种构象变化会影响多个器官和系统,包括口颌系统的硬组织和软组织。本研究的目的是通过计算机断层扫描描述40例SCD患者病例系列中患者的上下颌位置。为了确定患者的面部轮廓,进行了二维(2D)和三维(3D)麦克纳马拉和施泰纳头影测量描记。结果表明,在二维和三维分析中均有上颌前突的趋势。二维和三维评估之间没有统计学差异;此外,性别影响患者的上下颌位置,但仅在麦克纳马拉评估中。