Mello Sandra M F, Paulo C Araujo Roberto, Alves Cresio
Institute of Health Sciences, Federal University of Bahia, Salvador, Bahia, Brazil.
Oral Health Dent Manag. 2012 Sep;11(3):125-8.
The phenomenon of erythrocyte sickling observed in sickle cell anaemia is responsible for ischaemia and tissue infarction compromising several organs and systems including the mouth and face. This brief paper reports the case of a 17- year-old female with a complicated sickle cell anaemia, hypertension and paraplegia (after an ischaemic stroke at the age of six years). Oral examination revealed the absence of tooth 12, fractures of teeth 11, 21 and 22 (from trauma), active caries lesions in the enamel of teeth 36, 37 and 46, mucosal pallor, and a smooth tongue. Oral radiographs revealed bone rarefaction and trabecular bone coarsening. Dental surgeons and physicians should be aware of the general and oral abnormalities that can be present in individuals with sickle cell anaemia to allow for preventive measures and implementation of effective treatment options.
镰状细胞贫血中观察到的红细胞镰变现象是导致局部缺血和组织梗死的原因，这会损害包括口腔和面部在内的多个器官和系统。本文简要报告了一名17岁女性的病例，该患者患有复杂的镰状细胞贫血、高血压和截瘫（6岁时发生缺血性中风后）。口腔检查发现12号牙缺失，11、21和22号牙骨折（因外伤），36、37和46号牙釉质有活动性龋损，黏膜苍白，舌面光滑。口腔X光片显示骨质稀疏和骨小梁增粗。牙科医生和内科医生应了解镰状细胞贫血患者可能出现的全身和口腔异常情况，以便采取预防措施并实施有效的治疗方案。
