Gao Zhaoli, Li Xianhua, Peng Tao, Hu Zhao, Liu Jie, Zhen Junhui, Gao Yanxia
Department of Nephrology Department of Electromyography Room in Neurology Department of Pathology.
Medicine (Baltimore). 2018 Jun;97(25):e11160. doi: 10.1097/MD.0000000000011160.
We report a case of systemic lupus erythematosus (SLE) with Guillian-Barre syndrome (GBS) as the first symptom.
A 30-year-old Chinese female with numbness and inductance of lower extremities 2 months previously. The electromyographic and cerebrospinal fluid findings supported inflammatory demyelinating disease, and the renal biopsy findings and rheumatoid-related results considered systemic lupus erythematosus. The patient received treatment with glucocorticoids and cyclophosphamide. Two months after the treatment, the patient's limb numbness and weakness disappeared, and the urinary protein was decreased significantly.
Our case highlights the importance of the early diagnosis and treatment of SLE. Systemic lupus erythematosus is a multifactorial participant autoimmune systemic disease for which the clinical manifestations are complex and diverse. Glucocorticoid and cytotoxic drugs can be used in clinical treatment. If the disease is not diagnosed early, it could also delay treatment. Patients who receive an early diagnosis and appropriate treatment may have a better prognosis.
Data were collected from the patient's electronic medical records and the hospital laboratory medicine database.
我们报告一例以吉兰-巴雷综合征（GBS）为首发症状的系统性红斑狼疮（SLE）病例。
一名30岁中国女性，2个月前出现下肢麻木和感觉减退。肌电图和脑脊液检查结果支持炎性脱髓鞘疾病，肾活检结果及类风湿相关检查结果提示系统性红斑狼疮。患者接受了糖皮质激素和环磷酰胺治疗。治疗2个月后，患者肢体麻木和无力消失，尿蛋白显著减少。
我们的病例强调了SLE早期诊断和治疗的重要性。系统性红斑狼疮是一种多因素参与的自身免疫性全身性疾病，临床表现复杂多样。糖皮质激素和细胞毒性药物可用于临床治疗。若疾病未早期诊断，也可能延误治疗。早期诊断并接受适当治疗的患者预后可能更好。
数据收集自患者的电子病历和医院检验医学数据库。
