Villena-Suarez Juliana R, Vicente William, Taxa Luis, Cuéllar Luis, Nuñez-Butrón Maria T, Villegas Valeria, Castillo Miluska, Castañeda Carlos A
Instituto Nacional de Enfermedades Neoplásicas.
Rev Peru Med Exp Salud Publica. 2018 Jan-Mar;35(1):77-83. doi: 10.17843/rpmesp.2018.351.3602.
Tuberculosis (TB) is a major public health problem that, due to the clinical variability of its presentation, can be confused with cancer. The aim of this study was to identify the clinical-radiological characteristics and to describe the methodology that allowed to achieve a TB diagnosis in patients referred to the National Institute of Neoplastic Diseases (INEN) with a presumed diagnosis of cancer between 2014 and 2016. The study included 170 patients (52.4% men) with an average age of 41.1 years; 18% presented a history of contact with TB, and 5.9% had had the disease previously. The TB was pulmonary in 22.4% and extrapulmonary in 77.7% of patients. The most frequent symptoms were respiratory, tumor, weight loss, and neurological. The cancer diagnoses most frequently discarded were lymphoma, lung cancer, and brain cancer. The lesions that suggested a neoplasm indicated an advanced clinical stage in 63.5%. Therefore, it follows that the symptoms and images associated with TB can be confused with malignant neoplasms.
结核病是一个重大的公共卫生问题，由于其临床表现的变异性，可能会与癌症混淆。本研究的目的是确定临床放射学特征，并描述在2014年至2016年间被转诊至国家肿瘤疾病研究所（INEN）且初步诊断为癌症的患者中实现结核病诊断的方法。该研究纳入了170名患者（52.4%为男性），平均年龄为41.1岁；18%有结核病接触史，5.9%曾患过该病。22.4%的患者结核病为肺部病变，77.7%为肺外病变。最常见的症状是呼吸系统症状、肿瘤相关症状、体重减轻和神经系统症状。最常被排除的癌症诊断是淋巴瘤、肺癌和脑癌。提示肿瘤的病变在63.5%的病例中表明处于临床晚期。因此，可以得出结论，与结核病相关的症状和影像可能会与恶性肿瘤混淆。
