Garrocho-Rangel A, Manriquez-Olmos L, Flores-Velazquez J, Rosales-Berber M-A, Martinez-Rider R, Pozos-Guillen A
Facultad de Estomatologia, Universidad Autonoma de San Luis Potosi, Av. Dr. Manuel Nava #2, Zona Universitaria, C.P. 78290; San Luis Potosi, S.L.P. Mexico,
Med Oral Patol Oral Cir Bucal. 2018 Jul 1;23(4):e421-e428. doi: 10.4317/medoral.22328.
Craniosynostosis (CS) is a complex condition consisting of the early fusion of one or more cranial sutures in the intrauterine stage. The affected infant exhibits abnormal head shape at time of birth or shortly thereafter. It can be observed in normal individuals (non-syndromic CS or NSCS) or as a part of a multisystem syndrome. The purposes of the present article were to carry out a scoping review on Non-Syndromic CS and to discuss the most important findings retrieved.
The steps of this scoping review were as follows: first, to pose a research question; second, to identify relevant studies to answer the research question; third, to select and retrieve the studies; fourth, to chart the critical data, and finally, to collate, summarize, and report the results from the most important articles. Relevant articles published over a 20-year period were identified and retrieved from five Internet databases: PubMed; EMBASE; Cochrane Library; Google Scholar, and EBSCO.
Fourteen articles were finally included in the present scoping review. The following four most important clinical issues are discussed: (i) normal cranial development, clinical manifestations, and pathogenesis of NCSC; (ii) clinical evaluation of NCSC; (iii) treatment and post-surgical follow-up; and (iv) additional considerations.
NSCS may be present with associated head shapes. Multiple early surgical reconstructive options are currently available for the disorder. Pediatric Dentistry practitioners must be familiarized with this condition and form part of a multi-approach health team as those responsible for the opportune oral health care of the affected child.
颅缝早闭（CS）是一种复杂病症，表现为子宫内阶段一条或多条颅缝过早融合。患病婴儿在出生时或出生后不久即表现出头部形状异常。可在正常个体中观察到（非综合征性颅缝早闭或NSCS），也可作为多系统综合征的一部分出现。本文的目的是对非综合征性颅缝早闭进行范围综述，并讨论所检索到的最重要研究结果。
本范围综述的步骤如下：首先，提出研究问题；其次，识别回答该研究问题的相关研究；第三，选择并检索这些研究；第四，梳理关键数据，最后，整理、总结并报告最重要文章的结果。从五个互联网数据库中识别并检索了20年间发表的相关文章：PubMed、EMBASE、Cochrane图书馆、谷歌学术和EBSCO。
本范围综述最终纳入了14篇文章。讨论了以下四个最重要的临床问题：（i）非综合征性颅缝早闭的正常颅骨发育、临床表现和发病机制；（ii）非综合征性颅缝早闭的临床评估；（iii）治疗及术后随访；以及（iv）其他注意事项。
非综合征性颅缝早闭可能伴有相关的头部形状。目前针对该病症有多种早期手术重建方案。儿科牙科从业者必须熟悉这种情况，并作为多学科医疗团队的一员，负责为患病儿童提供适时的口腔保健。
