Abbanat D R, Godchaux W, Polychroniou G, Leadbetter E R
Biochem Biophys Res Commun. 1985 Jul 31;130(2):873-8. doi: 10.1016/0006-291x(85)90497-8.
Gliding bacteria of the genus Cytophaga synthesize sulfonolipids (1,2) that contain capnine (1-deoxy-15-methylhexadecasphinganine-1-sulfonic acid). Studies of the incorporation of radiolabeled compounds by C. johnsonae show that cysteate is utilized preferentially to both cystine and inorganic sulfate as a precursor of capnine sulfur and to both cystine and serine as a precursor of carbons 1 and 2 of capnine. The results are consistent with a pathway in which capnine is formed by condensation of cysteate with a fatty acyl CoA. Cystine, added as the sole sulfur source in the presence of glucose, provides the sulfur but not the carbon for capnine. Hence, these cells form cysteate not by direct oxidation of cystine (or cysteine), but by transfer of its sulfur to a different carbon compound.
噬纤维菌属的滑行细菌合成含有壬胺（1-脱氧-15-甲基十六烷鞘氨醇-1-磺酸）的磺脂（1,2）。对约翰逊噬纤维菌摄取放射性标记化合物的研究表明，作为壬胺硫的前体，半胱氨酸盐比胱氨酸和无机硫酸盐更优先被利用，作为壬胺碳1和碳2的前体，比胱氨酸和丝氨酸更优先被利用。这些结果与一种途径一致，即壬胺由半胱氨酸盐与脂肪酰辅酶A缩合形成。在葡萄糖存在的情况下，作为唯一硫源添加的胱氨酸为壬胺提供硫而非碳。因此，这些细胞形成半胱氨酸盐不是通过胱氨酸（或半胱氨酸）的直接氧化，而是通过将其硫转移到不同的碳化合物上。
