Effects of nicardipine on aldosterone release and pressor mechanisms.
作者信息
Elliott H L, Pasanisi F, Reid J L
出版信息
Br J Clin Pharmacol. 1985;20 Suppl 1(Suppl 1):99S-102S. doi: 10.1111/j.1365-2125.1985.tb05150.x.
Abstract
This study evaluated the effects of nicardipine, following intravenous infusion and oral administration, on the pressor and aldosterone responses to infused angiotensin II. Six healthy, normotensive male subjects were studied. Following administration of nicardipine, no significant change in blood pressure was seen. Nicardipine attenuated the pressor response produced by intravenous administration of angiotensin. Nicardipine did not inhibit the aldosterone response to angiotensin.
摘要
相似文献
1
Effects of nicardipine on aldosterone release and pressor mechanisms.
Br J Clin Pharmacol. 1985;20 Suppl 1(Suppl 1):99S-102S. doi: 10.1111/j.1365-2125.1985.tb05150.x.
2
Vascular and aldosterone responses to angiotensin II in normal humans: effects of nicardipine.
J Cardiovasc Pharmacol. 1985 Nov-Dec;7(6):1171-5. doi: 10.1097/00005344-198511000-00025.
3
Influence of nicardipine on blood pressure, renal function and plasma aldosterone in normotensive volunteers.
Br J Clin Pharmacol. 1985;20 Suppl 1(Suppl 1):88S-94S. doi: 10.1111/j.1365-2125.1985.tb05148.x.
4
Acute calcium entry blockade inhibits the blood pressure but not the hormonal responses to angiotensin II.
Eur J Clin Pharmacol. 1989;36(6):567-73. doi: 10.1007/BF00637737.
5
Effect of nifedipine on blood pressure and adrenocortical responses to trophic stimuli in humans.
J Cardiovasc Pharmacol. 1982;4 Suppl 3:S330-4.
6
Reduced pressor effect of angiotensin II and of noradrenaline in normal man following the oral administration of the calcium-antagonist nifedipine.
Eur J Clin Invest. 1982 Jun;12(3):263-7. doi: 10.1111/j.1365-2362.1982.tb01002.x.
7
Nicardipine did not activate renin-angiotensin-aldosterone system during isoflurane or sevoflurane anesthesia.
Can J Anaesth. 2000 Dec;47(12):1249-52. doi: 10.1007/BF03019876.
8
Effects of acute mild hypercalcemia or of the calcium antagonist nifedipine on cardiovascular responsiveness to norepinephrine or angiotensin II in normal humans.
J Cardiovasc Pharmacol. 1982;4 Suppl 3:S306-12.
9
The effect of the calcium antagonist nifedipine on pressor and aldosterone responses to angiotensin II in normal man.
Eur J Clin Pharmacol. 1983;24(3):315-21. doi: 10.1007/BF00610047.
10
Hormonal and renal responses to oral once-daily calcium entry blocker in normotensive and hypertensive persons.
J Cardiovasc Pharmacol. 1988 Apr;11(4):438-43. doi: 10.1097/00005344-198804000-00009.
引用本文的文献
1
Molecular and clinical investigations in patients with low-renin hypertension.
Clin Exp Nephrol. 2009 Feb;13(1):1-8. doi: 10.1007/s10157-008-0071-4. Epub 2008 Aug 15.
2
Nicardipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in the treatment of angina pectoris, hypertension and related cardiovascular disorders.
Drugs. 1987 Apr;33(4):296-345. doi: 10.2165/00003495-198733040-00002.
本文引用的文献
1
The mechanism of catecholamine release from the adrenal medulla and the role of calcium in stimulus-secretion coupling.
J Physiol. 1963 Jul;167(2):288-310. doi: 10.1113/jphysiol.1963.sp007150.
2
STIMULUS-SECRETION COUPLING IN A NEUROSECRETORY ORGAN: THE ROLE OF CALCIUM IN THE RELEASE OF VASOPRESSIN FROM THE NEUROHYPOPHYSIS.
J Physiol. 1964 Jul;172(1):1-18. doi: 10.1113/jphysiol.1964.sp007399.
3
A direct radio-immunoassay for aldosterone: significance of endogenous cortisol.
Neth J Med. 1980;23(2):79-83.
4
Calcium antagonists decrease adrenal and vascular responsiveness to angiotensin II in normal man.
Clin Sci (Lond). 1981 Dec;61 Suppl 7:65s-68s. doi: 10.1042/cs061065s.
5
Studies on aldosterone responsiveness to angiotensin II during clinical variations in calcium metabolism in normal man.
Clin Sci (Lond). 1982 Sep;63(3):325-8. doi: 10.1042/cs0630325.
6
The effect of the calcium antagonist nifedipine on pressor and aldosterone responses to angiotensin II in normal man.
Eur J Clin Pharmacol. 1983;24(3):315-21. doi: 10.1007/BF00610047.
7
Reduced pressor effect of angiotensin II and of noradrenaline in normal man following the oral administration of the calcium-antagonist nifedipine.
Eur J Clin Invest. 1982 Jun;12(3):263-7. doi: 10.1111/j.1365-2362.1982.tb01002.x.
8
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
Am Heart J. 1982 Dec;104(6):1346-50. doi: 10.1016/0002-8703(82)90166-1.
9
Dependence of aldosterone stimulation in adrenal glomerulosa cells on calcium uptake: effects of lanthanum nd verapamil.
Endocrinology. 1980 Nov;107(5):1345-53. doi: 10.1210/endo-107-5-1345.
10
Effect of nifedipine on blood pressure and adrenocortical responses to trophic stimuli in humans.
J Cardiovasc Pharmacol. 1982;4 Suppl 3:S330-4.
Zotero 插件