Sanches Brunno Cf, Laranja Walker W, Alonso João Cc, Rejowski Ronald F, Simões Fabiano A, Reis Leonardo O
Pontifical Catholic University of Campinas, PUC-Campinas, São Paulo, Brazil.
University of Campinas, PUC-Campinas, São Paulo, Brazil.
Int J Impot Res. 2018 Aug;30(4):158-162. doi: 10.1038/s41443-018-0039-1. Epub 2018 Jun 21.
The aim of this study is to assess the impact of objective (stretched) and subjective penile size in the erectile function in a urological check-up program on a cross-sectional study including 689 men aged 35-70 years. IIEF-5 questionnaire, physical examination (penile length, prostate volume, blood pressure, body mass index-BMI), metabolic syndrome (MS), comorbidities, habits (sexual intercourse frequency, physical activity, alcohol, and tobacco use), level of education, serum glucose, total testosterone, estradiol, PSA, lipid profile, and self-perceptions (ejaculation time and subjective penile size) were examined in multivariate models using logistic and linear regressions. Penile objective mean length was 13.08 cm ± 2.32 and 67 (9.72%) patients referred small penis self-perception. Seventy-six (11.03%) participants had severe erectile dysfunction (ED), 75 (10.88%) had mild to moderate and moderate ED, 112 (16.25%) had mild ED and 426 (61.83%) had no ED. Risk factors for ED that held statistical significance were self-perceived small penis (OR = 2.23, 95% CI 1.35-3.69, p = .0017), sexual intercourse frequency (per week) (OR = 0.45, 95% CI 0.38-0.52, p < .0001), satisfactory ejaculation time (no vs. yes, OR = 2.06, 95% CI 1.46-2.92, p < .0001), comorbidity (yes vs. no, OR = 2.01, 95% CI 1.46-2.76, p < .0001), age >65 years (OR = 2.93, 95% CI 1.53-5.61, p < .0001), tobacco use (yes vs. no, OR = 1.41, 95% CI 1.02-1.96, p < .0375), regular physical activity (no vs. yes, OR = 1.59, 95% CI 1.13-2.23, p < .0083), serum total testosterone < 200 ng/dl (OR = 3.48, 95% CI 1.69-7.16, p = 0.0009), serum glucose > 100 mg/dl (OR = 1.69, 95% CI 1.18-2.43, p = 0.0044) and systolic blood pressure > 130 mmHg (OR = 1.60, 95% CI 1.16-2.19, p = 0.0037). Results suggest that in addition to previously reported risk factors, patient's subjective impressions of penile size negatively impacts sexual life in about 10% of men considered healthy, while objective penile length does not play significant role in erectile function.
本研究旨在通过一项横断面研究,评估在一个泌尿外科检查项目中,客观(拉伸后)阴茎大小和主观阴茎大小对689名年龄在35至70岁男性勃起功能的影响。使用逻辑回归和线性回归的多变量模型对国际勃起功能指数-5问卷、体格检查(阴茎长度、前列腺体积、血压、体重指数-BMI)、代谢综合征(MS)、合并症、习惯(性交频率、体育活动、饮酒和吸烟)、教育程度、血清葡萄糖、总睾酮、雌二醇、前列腺特异性抗原、血脂谱以及自我认知(射精时间和主观阴茎大小)进行了检查。阴茎客观平均长度为13.08厘米±2.32,67名(9.72%)患者自述阴茎尺寸小。76名(11.03%)参与者患有严重勃起功能障碍(ED),75名(10.88%)患有轻度至中度ED,112名(16.25%)患有轻度ED,426名(61.83%)没有ED。具有统计学意义的ED危险因素包括自我感觉阴茎小(比值比[OR]=2.23,95%置信区间[CI]1.35 - 3.69,p = 0.0017)、性交频率(每周)(OR = 0.45,95% CI 0.38 - 0.52,p < 0.0001)、射精时间满意(否与是,OR = 2.06,95% CI 1.46 - 2.92,p < 0.0001)、合并症(是与否,OR = 2.01,95% CI 1.46 - 2.76,p < 0.0001)、年龄>65岁(OR = 2.93,95% CI 1.53 - 5.61,p < 0.0001)、吸烟(是与否,OR = 1.41,95% CI 1.02 - 1.96,p < 0.0375)、规律体育活动(否与是,OR = 1.59,95% CI 1.13 - 2.23,p < 0.0083)、血清总睾酮<200 ng/dl(OR = 3.48,95% CI 1.69 - 7.16,p = 0.0009)、血清葡萄糖>100 mg/dl(OR = 1.69,95% CI 1.18 - 2.43,p = 0.0044)以及收缩压>130 mmHg(OR = 1.60,95% CI 1.16 - 2.19,p = 0.0037)。结果表明,除了先前报道的危险因素外,患者对阴茎大小的主观印象对约10%被认为健康的男性的性生活有负面影响,而客观阴茎长度在勃起功能中不起重要作用。