Stratingh Institute for Chemistry, University of Groningen, Nijenborgh 4, 9747 AG, Groningen, The Netherlands.
Chem Commun (Camb). 2018 Jul 10;54(56):7725-7745. doi: 10.1039/c8cc02937g.
The structural complexity of lignocellulose offers unique opportunities for the development of entirely new, energy efficient and waste-free pathways in order to obtain valuable bio-based building blocks. Such sustainable catalytic methods - specifically tailored to address the efficient conversion of abundant renewable starting materials - are necessary to successfully compete, in the future, with fossil-based multi-step processes. In this contribution we give a summary of recent developments in this field and describe our "cleave and couple" strategy, where "cleave" refers to the catalytic deconstruction of lignocellulose to aromatic and aliphatic alcohol intermediates, and "couple" involves the development of novel, sustainable transformations for the formation of C-C and C-N bonds in order to obtain a range of attractive products from lignocellulose.
木质纤维素的结构复杂性为开发全新的、节能且无废物的途径提供了独特的机会，以便获得有价值的基于生物的构建块。这种可持续的催化方法——专门针对高效转化丰富的可再生起始原料进行了定制——对于未来成功与基于化石的多步工艺竞争是必要的。在本文中，我们总结了该领域的最新进展，并描述了我们的“裂解和偶联”策略，其中“裂解”是指木质纤维素的催化解构为芳香族和脂肪族醇中间体，“偶联”涉及开发新型的可持续转化方法，以形成 C-C 和 C-N 键，从而从木质纤维素中获得一系列有吸引力的产品。
