Greenberg A H
Biomed Pharmacother. 1985;39(1):4-6.
Natural antibody has been proposed as a mediator of T-independent (natural) resistance to tumors and microbial pathogens. In this article, it is argued that the "priming" of the B cell repertoire by ubiquitous microorganisms and autoantigens results in natural antibody production and this response offers a survival advantage for the host as a consequence of the participation of these antibodies in natural resistance.
天然抗体已被认为是对肿瘤和微生物病原体的非依赖T细胞(天然)抗性的介质。在本文中,有人认为,普遍存在的微生物和自身抗原对B细胞库的“启动”导致天然抗体的产生,并且由于这些抗体参与天然抗性,这种反应为宿主提供了生存优势。