Eshuis Wietse J, van Berge Henegouwen Mark I, Draaisma Werner A, Gisbertz Suzanne S
Department of Surgery, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands.
Department of Surgery, Jeroen Bosch Ziekenhuis, 's Hertogenbosch, The Netherlands.
Updates Surg. 2018 Jun;70(2):197-205. doi: 10.1007/s13304-018-0553-1. Epub 2018 Jun 20.
The objective of this study is to describe the compliance to D2 lymphadenectomy in laparoscopic gastrectomy. Radical partial or total gastrectomy with modified D2 lymphadenectomy is the standard of care for locally advanced gastric cancer. It is unclear whether compliance to D2 lymphadenectomy in laparoscopy is comparable to that in open surgery. A review of the literature was performed and results are described in a descriptive review. Available randomized trials are mostly performed for early gastric cancer, for which formal D2 lymphadenectomy is usually not required. Most trials report no differences in number of retrieved lymph nodes between open and laparoscopic gastrectomy. Only one trial used adherence to D2 lymphadenectomy as primary outcome parameter, and found no difference between laparoscopic and open gastrectomy. Results from randomized trials in advanced gastric cancer are awaited. In the meantime, the laparoscopic approach can be used in experienced centers.
本研究的目的是描述腹腔镜胃癌根治术中D2淋巴结清扫的依从性。根治性部分或全胃切除术联合改良D2淋巴结清扫是局部进展期胃癌的标准治疗方法。目前尚不清楚腹腔镜下D2淋巴结清扫的依从性是否与开放手术相当。我们进行了文献综述,并以描述性综述的形式呈现结果。现有的随机试验大多针对早期胃癌开展,而早期胃癌通常不需要进行正规的D2淋巴结清扫。大多数试验报告称,开放和腹腔镜胃癌根治术之间清扫出的淋巴结数量没有差异。只有一项试验将D2淋巴结清扫的依从性作为主要结局参数,结果发现腹腔镜和开放胃癌根治术之间没有差异。我们正在等待晚期胃癌随机试验的结果。与此同时,腹腔镜手术方法可在经验丰富的中心使用。