Zhang Ya-Li, Diao Yun-Yun, Yang Hai-Ying, Wang Jia-Xu, Jiang Huan-Huan, Li Ying-Ming
Department of Obstetrics, the Second Affiliated Hospital, Hebei North University, Xuanhua 075100, China.
Department of Function, the Second Affiliated Hospital, Hebei North University, Xuanhua 075100, China.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2017 Apr 8;33(4):342-345. doi: 10.12047/j.cjap.5520.2017.083.
To observe the abnormality of the electrocardiogram (ECG) and the characteristics of arrhythmia in the early stage of older pregnant women and to record the late outcome of atrial and ventricular arrhythmia.
Two hundrend and ninty pregnant women were divided into 3 groups by age under 35 group, 3539 group and 4045 group. The ECG waveform was analyzed systematically when the patients were subjected to routine ECG examination and abnormal changes of ECG were collected and recorded, including ST segment changes, various arrhythmias, etc. Then the recovery and deterioration rate of atrial, ventricular arrhythmia was recorded.
The incidence of arrhythmia in 3539 group and 4045 group was significantly higher than under 35 group (<0.05); the incidence of abnormal ST section in 3539 group and 4045 group was significantly higher than under 35 group(<0.05); and the incidence of widened QRS wave in 4045 group was higher than under 35 group (<0.05). The incidence of sinus tachycardia, sinus irregularityand atrial premature beats in 3539 group and 4045 group was obviously lower than that under 35 group (<0.05); the incidence of Paroxysmal supraventricular tachycardia in 4045 group was obviously higher than under 35 group (<0.05) and the incidence of ventricular premature beat and atrial fibrillation in 3539 group and 4045 group was significantly higher than under 35 group (<0.05). The recovery rate of atrial arrhythmia in 4045 group was obviously lower than under 35 group (<0.05);the exacerbation rate of trial and ventricular arrhythmia in 4045 group was obviously higher than over 35 group (<0.05). The incidences of IUGR in 3539 group and 4045 group with abnormal ECG was obviously higher than under 35 group and 3539 group with normal ECG; The incidences of fetal distress in 3539 year-old group and 40~45 year-old group with abnormal ECG was obviously higher than under 35 group(<0.05).
There is a positive correlation between the old age and the incidence of arrhythmia in the early stage of pregnancy, and old age factors can reduce the recovery rate but increase the incidence of deterioration of arrhythmia. And older pregnant women with abnormal ECG have undesirable effect to perinatal infant.
观察高龄孕妇早期心电图（ECG）异常及心律失常特点，并记录房性和室性心律失常的后期转归。
290例孕妇按年龄分为<35岁组、35～39岁组和40～45岁组。患者进行常规心电图检查时系统分析心电图波形，收集并记录心电图异常变化，包括ST段改变、各种心律失常等。然后记录房性、室性心律失常的恢复及恶化率。
35～39岁组和40～45岁组心律失常发生率显著高于<35岁组（<0.05）；35～39岁组和40～45岁组ST段异常发生率显著高于<35岁组（<0.05）；40～45岁组QRS波增宽发生率高于<35岁组（<0.05）。35～39岁组和40～45岁组窦性心动过速、窦性心律不齐及房性早搏发生率明显低于<35岁组（<0.05）；40～45岁组阵发性室上性心动过速发生率明显高于<35岁组（<0.05），35～39岁组和40～45岁组室性早搏及心房颤动发生率显著高于<35岁组（<0.05）。40～45岁组房性心律失常恢复率明显低于<35岁组（<0.05）；40～45岁组房性和室性心律失常恶化率明显高于>35岁组（<0.05）。心电图异常的35～39岁组和40～45岁组胎儿生长受限发生率明显高于心电图正常的<35岁组和35～39岁组；心电图异常的35～39岁组和40～45岁组胎儿窘迫发生率明显高于<35岁组（<0.05）。
妊娠早期年龄与心律失常发生率呈正相关，年龄因素可降低心律失常恢复率但增加恶化发生率。心电图异常的高龄孕妇对围产儿有不良影响。
