儿童时期的体重指数与青少年时期饮食障碍特征的发展。
Childhood body mass index and development of eating disorder traits across adolescence.
机构信息
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
出版信息
Eur Eat Disord Rev. 2018 Sep;26(5):462-471. doi: 10.1002/erv.2612. Epub 2018 Jun 21.
OBJECTIVE
Understanding the role of premorbid body mass index (BMI) in the emergence of eating disorders may be key to identifying effective prevention strategies. We explore relations between BMI and eating disorders traits in young twins.
METHOD
The effect of BMI at age 9/12 and 15 on eating disorder traits measured using the Eating Disorders Inventory-2 (EDI) at ages 15 and 18 was examined using bivariate modelling in a longitudinal population sample of Swedish twins.
RESULTS
The correlation between BMI and EDI within individuals was stable across all ages and remained significant after adjusting for later BMI. Bivariate analysis indicated significant positive genetic correlations between BMI ages 9/12 and 15 and subsequent EDI scores. The relationship remained significant for BMI age 9/12 and EDI age 15 in the adjusted model, indicating a longitudinal association.
CONCLUSION
Our results have implications for conceptualizing the interrelation of BMI and eating disorders across childhood and adolescence.
目的
了解发病前体重指数（BMI）在饮食障碍出现中的作用可能是确定有效预防策略的关键。我们探讨了青少年双胞胎中 BMI 与饮食障碍特征之间的关系。
方法
使用 Eating Disorders Inventory-2（EDI）在瑞典双胞胎纵向人群样本中，采用双变量模型检验 9/12 岁和 15 岁时 BMI 对 15 岁和 18 岁时饮食障碍特征的影响。
结果
个体内 BMI 与 EDI 之间的相关性在所有年龄段都保持稳定，并且在调整后 BMI 后仍然显著。双变量分析表明，9/12 岁和 15 岁时 BMI 与随后的 EDI 评分之间存在显著的正遗传相关性。在调整后的模型中，9/12 岁时的 BMI 与 EDI 年龄 15 之间的关系仍然显著，表明存在纵向关联。
结论
我们的研究结果对于理解儿童期和青春期 BMI 与饮食障碍的相互关系具有重要意义。
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