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1990-2015 年医疗技术创新对患者结局的影响:一项医师调查的结果。

The Effect of Medical Technology Innovations on Patient Outcomes, 1990-2015: Results of a Physician Survey.

机构信息

1 RTI Health Solutions, Research Triangle Park, North Carolina.

2 National Pharmaceutical Council, Washington, DC.

出版信息

J Manag Care Spec Pharm. 2019 Jan;25(1):66-71. doi: 10.18553/jmcp.2018.18083. Epub 2018 Jun 21.

Abstract

BACKGROUND

Developments in diagnostics, medical devices, procedures, and prescription drugs have increased life expectancy and quality of life after diagnosis for many diseases. Previous research has shown that, overall, increased investment in medical technology has led to increased health outcomes. In addition, the value of investment in specific innovations, particularly in new pharmaceuticals or biopharmaceuticals, has frequently been shown through an evaluation of the associated health outcomes and costs. Value assessments for all medical technologies and interventions are an important consideration in current debates on access and affordability of health care in the United States.

OBJECTIVE

To identify practicing physician impressions of the historical effect of postdiagnosis innovations in medical technology on patient outcomes within the 8 health conditions that have the largest effect on health in the United States.

METHODS

National statistics were used to identify the 8 conditions responsible for the most mortality and morbidity within the United States between 1990 and 2014. A physician survey was developed for each major condition to obtain physician opinion on the extent to which pharmaceuticals and biopharmaceuticals, medical devices, diagnostics, and surgical procedures contributed to improvements in postdiagnosis mortality and morbidity outcomes over the evaluated period. Respondents were provided with a fifth category, "cannot allocate," to account for postdiagnosis outcome gains resulting from other factors such as public health interventions.

RESULTS

The conditions identified as having the greatest effect on morbidity and mortality since 1990 were breast cancer, ischemic heart disease, human immunodeficiency virus infection, diabetes, unipolar depression, chronic obstructive pulmonary disease, cerebrovascular disease, and lung cancer. After excluding other factors, physicians specializing in these conditions, with a mean of 21.4 years in practice, considered pharmaceuticals and biopharmaceuticals as having the greatest postdiagnosis effect across all 8 conditions, with 56% of outcome gains attributed to this innovation category. Diagnostics was the second biggest contributor at 20%.

CONCLUSIONS

Physician perceptions indicated that attention should be paid to value assessments of innovative diagnostics, devices, and surgical procedures, as well as to pharmaceuticals and biopharmaceuticals, before goals for allocating health care expenditures among the different innovations are determined.

DISCLOSURES

Funding for this study was provided by the National Pharmaceutical Council, a health policy research group that receives its funding from biopharmaceutical manufacturers. Wamble is employed by RTI Health Solutions, which received funding from the National Pharmaceutical Council to conduct this research. Ciarametaro and Dubois are employed by the National Pharmaceutical Council.

摘要

背景

诊断技术、医疗器械、医疗程序和处方药物的发展提高了许多疾病的诊断后预期寿命和生活质量。以往的研究表明,总体而言,对医疗技术的投资增加导致了健康结果的改善。此外,通过评估相关的健康结果和成本,经常可以证明特定创新,特别是新的药品或生物制药的投资价值。对所有医疗技术和干预措施的价值评估是当前美国医疗保健可及性和负担能力辩论的重要考虑因素。

目的

确定在对美国健康影响最大的 8 种健康状况中,医生对诊断后医疗技术创新对患者结局的历史影响的看法。

方法

利用国家统计数据确定了 1990 年至 2014 年期间导致美国死亡率和发病率最高的 8 种疾病。为每个主要疾病开发了医生调查,以获取医生对药品和生物制药、医疗器械、诊断和手术程序在评估期间对改善诊断后死亡率和发病率结局的看法。为了说明公共卫生干预等其他因素导致的诊断后结果的提高,受访者还提供了第五个类别“无法分配”。

结果

自 1990 年以来,被确定为对发病率和死亡率影响最大的疾病是乳腺癌、缺血性心脏病、人类免疫缺陷病毒感染、糖尿病、单相抑郁症、慢性阻塞性肺疾病、脑血管疾病和肺癌。在排除其他因素后,专门研究这些疾病的医生,平均有 21.4 年的实践经验,认为药品和生物制药对所有 8 种疾病的诊断后效果最大,其中 56%的结果提高归因于这一创新类别。诊断是第二大贡献者,占 20%。

结论

医生的看法表明,在确定不同创新之间分配医疗保健支出的目标之前,应该注意对创新诊断、设备和手术程序以及药品和生物制药的价值评估。

披露

本研究的资金由国家制药理事会提供,这是一个健康政策研究小组,其资金来自生物制药制造商。Wamble 受雇于 RTI 健康解决方案公司,该公司从国家制药理事会获得资金进行这项研究。Ciarametaro 和 Dubois 受雇于国家制药理事会。

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