Zueva I B, Krivonosov D S, Buch A V, Kim Yu V
Saint-Petersburg medical-social Institute, Saint-Petersburg, Russia; St. Petersburg clinical scientific and practical center for specialized types of medical care, Saint-Petersburg, Russia.
Saint-Petersburg medical-social Institute, Saint-Petersburg, Russia; Almazov National medical research center, Saint-Petersburg, Russia.
Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(5):18-22. doi: 10.17116/jnevro20181185118.
To study the effect of therapy with cytoflavin on cognitive function in patients with metabolic syndrome (MS).
The randomized controlled open study included 156 patients with MS. The mean age was 41.27±5.16 years. The duration of observation was 16 weeks. The main group of patients (n=78) received cytoflavin in the dose of 2 tablets 2 times a day. Patients in the control group (n=78) received basic therapy. All patients underwent neuropsychological testing at baseline, after 2 months and at the end of the study. Cognitive evoked potentials (Р300) were recorded to assess cognitive functions. The levels of plasma glucose and lipid profile were measured.
Cytoflavin improved cognitive functions. Two months after treatment, the results of neuropsychological testing and electrophysiological study were better in the main group compared to the control group.
研究细胞黄素治疗对代谢综合征（MS）患者认知功能的影响。
这项随机对照开放研究纳入了156例MS患者。平均年龄为41.27±5.16岁。观察期为16周。主要患者组（n = 78）接受剂量为每日2次、每次2片的细胞黄素治疗。对照组（n = 78）患者接受基础治疗。所有患者在基线、2个月后和研究结束时均接受神经心理学测试。记录认知诱发电位（P300）以评估认知功能。测量血浆葡萄糖水平和血脂谱。
细胞黄素改善了认知功能。治疗2个月后，主要组的神经心理学测试和电生理研究结果优于对照组。
