Kitahara Miyuki, Hozumi Yasuo, Asada Rio, Sawa Aya, Saito Hitoaki, Iijima Tatsuo
Department of Breast Surgery, Ibaraki Prefectural Central Hospital and Cancer Center, Kasama, Japan.
Department of Pathology, Ibaraki Prefectural Central Hospital and Cancer Center, Kasama, Japan.
Case Rep Oncol. 2018 May 29;11(2):318-322. doi: 10.1159/000489391. eCollection 2018 May-Aug.
Intramammary metastasis of renal cell carcinoma (RCC) is extremely rare, accounting for only 1.5% of all intramammary metastases. Distinguishing intramammary metastases from benign tumors and breast cancer is clinically problematic. Some patients undergo excessive surgery after a misdiagnosis of breast cancer instead of a mammary tumor. We performed a core needle biopsy (CNB) of a breast mass that developed in a 71-year-old woman after surgeries for bilateral RCC and breast cancer, leading to a diagnosis of intramammary metastasis of RCC. In this case, the CNB and immunohistochemical examination were critical for reaching a definitive diagnosis. We conclude that, when examining patients with mammary tumors, establishing their history of malignant tumors may help diagnose intramammary metastasis and select the best treatment strategy.
肾细胞癌（RCC）的乳腺内转移极为罕见，仅占所有乳腺内转移的1.5%。在临床上，区分乳腺内转移瘤与良性肿瘤及乳腺癌存在困难。一些患者在被误诊为乳腺癌而非乳腺肿瘤后接受了过度手术。我们对一名71岁女性在双侧RCC和乳腺癌手术后出现的乳腺肿块进行了粗针穿刺活检（CNB），最终诊断为RCC的乳腺内转移。在该病例中，CNB和免疫组化检查对于明确诊断至关重要。我们得出结论，在检查乳腺肿瘤患者时，了解其恶性肿瘤病史可能有助于诊断乳腺内转移并选择最佳治疗策略。
