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眼球摘除术后美学效果良好的晚期脉络膜黑色素瘤:一例报告。

Advanced choroidal melanoma with a desirable aesthetic outcome after enucleation: A case report.

作者信息

Terzidou Chryssa, Trivli Alexandra, Dalianis Georgios, Apessou Dimitra, Spandidos Demetrios A, Goulielmos George N

机构信息

Department of Ophthalmology, Konstantopouleio-Patission General Hospital, 14233 Nea Ionia, Athens, Greece.

Department of Pathology, Konstantopouleio-Patission General Hospital, 14233 Nea Ionia, Athens, Greece.

出版信息

Oncol Lett. 2018 Jul;16(1):511-514. doi: 10.3892/ol.2018.8661. Epub 2018 May 8.

Abstract

Choroidal melanoma is a rare ocular tumor. The present study reports the case of a 66-year-old male who presented with chronic headache and progressive visual loss. Physical eye examination and combined A- and B-mode ultrasonography detected choroidal melanoma. Due to tumor characteristics the eye was enucleated restoring the orbital volume with a 22 mm intraorbital bioceramic sphere implant. The eye was subjected to histopathological examination that confirmed the choroidal melanoma, 2 cm in diameter and 0.8 cm in elevation, occupying almost half of the globe. Microscopically, the neoplasm comprises mostly of epithelioid cells and fewer Type B spindle cells, with intense pigmentation. AJCC staging for the melanoma was T4b. The patient was fitted with an artificial eye after enucleation. Thirteen months after initial diagnosis, liver metastases were confirmed during his scheduled follow-up.

摘要

脉络膜黑色素瘤是一种罕见的眼部肿瘤。本研究报告了一例66岁男性患者,该患者表现为慢性头痛和进行性视力丧失。眼部体格检查及A、B型超声联合检查发现脉络膜黑色素瘤。由于肿瘤特征,该眼被摘除,并植入一个22毫米的眶内生物陶瓷球植入物以恢复眼眶容积。该眼进行了组织病理学检查,证实为脉络膜黑色素瘤,直径2厘米,隆起0.8厘米,几乎占据眼球的一半。显微镜下,肿瘤主要由上皮样细胞组成,B型梭形细胞较少,色素沉着明显。该黑色素瘤的美国癌症联合委员会(AJCC)分期为T4b。患者摘除眼球后佩戴了义眼。初次诊断13个月后,在 scheduled follow-up 期间确认发生了肝转移。

scheduled follow-up 直译为“预定的随访”,此处可能需要结合上下文准确理解其具体含义来进一步优化表述,但仅按要求进行翻译就是这样。

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