Soliman Noha, Mamdouh Diaa, Elkordi Aisha
UCL Institute of Ophthalmology, London EC1V 9EL, UK.
National Institute for Health Research Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital NHS Foundation Trust, UCL Institute of Ophthalmology, London EC1V 2PD, UK.
Medicines (Basel). 2023 Jan 5;10(1):11. doi: 10.3390/medicines10010011.
Choroidal melanoma is a rare malignant tumour, yet it is the most common primary intra-ocular neoplasm and second on the list of top ten most malignant melanoma sites in the body. Clinical presentation can be non-specific and includes photopsia, floaters, progressive visual field loss, and blurry vision. The tumour is quite often diagnosed clinically during fundus examination; however, the most valued diagnostic tests are A- and B-scan ultrasonography (US). Several factors affect prognosis, including the patient's age, tumour size, histological features, and presence of metastases. Still, with primary treatment and tight surveillance, around 50% of choroidal melanoma patients metastasise.
脉络膜黑色素瘤是一种罕见的恶性肿瘤,但它是最常见的原发性眼内肿瘤,在人体十大最恶性黑色素瘤部位中排名第二。临床表现可能不具特异性,包括闪光感、飞蚊症、进行性视野缺损和视力模糊。该肿瘤常在眼底检查时临床诊断;然而,最有价值的诊断检查是A超和B超超声检查(US)。有几个因素会影响预后,包括患者年龄、肿瘤大小、组织学特征和转移情况。不过,经过初步治疗和严密监测,仍有大约50%的脉络膜黑色素瘤患者会发生转移。