Jawed Shafaq, Zubair Ujala, Zubair Zarafshan
MBBS, Jinnah Sindh Medical University (SMC).
Medicine, Dow University of Health Sciences (DUHS), Karachi, Pakistan.
Cureus. 2018 Apr 18;10(4):e2504. doi: 10.7759/cureus.2504.
Mitral valve regurgitation (MVR) is the reverse passage of blood through the mitral valve when the valve fails to close during ventricle contraction. Transcatheter mitral valve repair and replacement (TMVR) is a recent technology that can benefit MVR patients as an alternative, minimally invasive, and safer solution than conventional open-heart surgical approaches. TMVR uses a catheter guided by ultrasonography to replace or repair the defective valve and has provided better clinical outcomes, decreased hospital stay, and reduced mortality rates. Therefore, TVMR should be made possible worldwide, especially in South-Asian regions where heart conditions such as atrial fibrillation and stroke are major contributing factors in a high postoperative mortality rate.
二尖瓣反流(MVR)是指在心室收缩时二尖瓣无法关闭,导致血液逆向通过二尖瓣。经导管二尖瓣修复和置换术(TMVR)是一项最新技术,作为一种替代方案,它比传统的开胸手术方法更微创、更安全,能使二尖瓣反流患者受益。TMVR使用由超声引导的导管来置换或修复有缺陷的瓣膜,并已带来了更好的临床效果、缩短了住院时间并降低了死亡率。因此,经导管二尖瓣置换术应在全球范围内普及,尤其是在南亚地区,那里心房颤动和中风等心脏疾病是导致术后死亡率居高不下的主要因素。