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基于蒙特卡罗模拟算法的高能治疗光子笔形束注量评估

Pencil-Beam Fluence Evaluation Based on Monte Carlo Simulations Algorithm of High Energetic Treatment Photons.

作者信息

Donya Hossam

机构信息

Department of Physics, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.

Department of Physics, Faculty of Science, Menoufia University, Shibin El-Koom, Egypt.

出版信息

J Med Signals Sens. 2018 Apr-Jun;8(2):81-86.

Abstract

BACKGROUND

The accurate calculation of doses during external radiotherapy sessions is necessary. Recently, the models used for this purpose have been the point kernel, pencil-beam, and collapsed cone superposition/convolution combination models.

METHODS

In this study, it is aimed to determine point/pencil-beam kernels to be used in dose calculations. For this purpose, tallying pencil-beam fluence based on Monte Carlo (MC) simulations is investigated by scoring a volume of interest centered in a cubic water phantom at a depth of 10 cm and the irradiated field of 10 cm × 10 cm. The fluence is calculated for each mono-energetic photon ranging from 0.25-6 MV at increments of 250 keV.

RESULTS

The output of the four fluence kernels along the depth Z around the central axis is categorized for both the primary and secondary photons and electrons. Here, a database for pencil-beam kernels is established for each category. For validation purposes, other MC simulations are carried out for fluence calculations as produced by the predetermined poly-energetic spectra for a Varian 6 MV linear accelerator.

CONCLUSIONS

The net results show a good fit of the two convoluted fluence spectra quantities for both mono-energetic and poly-energetics-based simulations except little singular peaks.

摘要

背景

在体外放射治疗过程中准确计算剂量是必要的。最近,用于此目的的模型有点核、笔形束和坍缩锥叠加/卷积组合模型。

方法

在本研究中,旨在确定用于剂量计算的点/笔形束核。为此,通过对位于10 cm深度的立方水体模中心且辐照野为10 cm×10 cm的感兴趣体积进行评分,研究基于蒙特卡罗(MC)模拟计算笔形束注量。对能量范围从0.25 - 6 MV、增量为250 keV的每个单能光子计算注量。

结果

对沿中心轴深度Z的四个注量核的输出按初级和次级光子及电子进行分类。在此,为每个类别建立了笔形束核数据库。为进行验证,针对瓦里安6 MV直线加速器的预定多能谱产生的注量计算开展了其他MC模拟。

结论

净结果表明,除了一些小的奇异峰值外,单能和基于多能的模拟的两个卷积注量谱量拟合良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/161a/5992905/c6be21063d06/JMSS-8-81-g005.jpg

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