Donya Hossam
Department of Physics, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.
Department of Physics, Faculty of Science, Menoufia University, Shibin El-Koom, Egypt.
J Med Signals Sens. 2018 Apr-Jun;8(2):81-86.
The accurate calculation of doses during external radiotherapy sessions is necessary. Recently, the models used for this purpose have been the point kernel, pencil-beam, and collapsed cone superposition/convolution combination models.
In this study, it is aimed to determine point/pencil-beam kernels to be used in dose calculations. For this purpose, tallying pencil-beam fluence based on Monte Carlo (MC) simulations is investigated by scoring a volume of interest centered in a cubic water phantom at a depth of 10 cm and the irradiated field of 10 cm × 10 cm. The fluence is calculated for each mono-energetic photon ranging from 0.25-6 MV at increments of 250 keV.
The output of the four fluence kernels along the depth Z around the central axis is categorized for both the primary and secondary photons and electrons. Here, a database for pencil-beam kernels is established for each category. For validation purposes, other MC simulations are carried out for fluence calculations as produced by the predetermined poly-energetic spectra for a Varian 6 MV linear accelerator.
The net results show a good fit of the two convoluted fluence spectra quantities for both mono-energetic and poly-energetics-based simulations except little singular peaks.
在体外放射治疗过程中准确计算剂量是必要的。最近,用于此目的的模型有点核、笔形束和坍缩锥叠加/卷积组合模型。
在本研究中,旨在确定用于剂量计算的点/笔形束核。为此,通过对位于10 cm深度的立方水体模中心且辐照野为10 cm×10 cm的感兴趣体积进行评分,研究基于蒙特卡罗(MC)模拟计算笔形束注量。对能量范围从0.25 - 6 MV、增量为250 keV的每个单能光子计算注量。
对沿中心轴深度Z的四个注量核的输出按初级和次级光子及电子进行分类。在此,为每个类别建立了笔形束核数据库。为进行验证,针对瓦里安6 MV直线加速器的预定多能谱产生的注量计算开展了其他MC模拟。
净结果表明,除了一些小的奇异峰值外,单能和基于多能的模拟的两个卷积注量谱量拟合良好。