Smitha K A, Arun K M, Rajesh P G, Joel Suresh E, Venkatesan Ramesh, Thomas Bejoy, Kesavadas Chandrasekharan
Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrun, Kerala, India.
Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrun, Kerala, India.
Magn Reson Imaging. 2018 Nov;53:1-6. doi: 10.1016/j.mri.2018.06.013. Epub 2018 Jun 18.
Ensuring patient comfort and compliance by emphasizing reduced time frame for image acquisition, without compromising image quality is the key aspect with functional MRI examination. Multiband resting state fMRI (MB-rsfMRI) is a fairly new technique that potentially shortens MR image acquisition time by providing increased number of time points. The study aims to compare signal characteristics as well as the functional connectivity using conventional resting-state fMRI (rsfMRI) with that of MB-rsfMRI technique.
9 healthy volunteers have prospectively undergone conventional resting-state fMRI and Multiband rsfMRI scanning technique in a 3T GE scanner (Discovery MR750w™). We compared the temporal SNR (tSNR) of conventional rs-fMRI with that of MB-rsfMRI. We looked at the language network connectivity and small world network characteristics from graph theoretical measures to compare the two techniques.
We computed the tSNR of conventional resting-state fMRI (rsfMRI) and MB-rsfMRI technique. A strong positive correlation was seen between graph theoretical measures from MB-rsfMRI and conventional rsfMRI (Pearson Correlation, r = 0.99). Both techniques showed similar small world network characteristics in healthy controls.
The present study demonstrates negligible differences between the conventional-rsfMRI and MB-rsfMRI acquisitions on the computed graph theoretic measures. Accordingly current analysis proves that MB-rs-fMRI may be used as a time reducing acquisition technique that enables mapping of functional connectivity with similar outcome as conventional rs-fMRI in healthy subjects.
在不影响图像质量的前提下，通过缩短图像采集时间来确保患者舒适度和依从性是功能磁共振成像检查的关键所在。多频段静息态功能磁共振成像（MB-rsfMRI）是一项相当新的技术，它通过增加时间点数量，有可能缩短磁共振图像采集时间。本研究旨在比较传统静息态功能磁共振成像（rsfMRI）与MB-rsfMRI技术的信号特征以及功能连接性。
9名健康志愿者前瞻性地在一台3T通用电气扫描仪（Discovery MR750w™）上接受了传统静息态功能磁共振成像和多频段静息态功能磁共振成像扫描技术。我们比较了传统rs-fMRI与MB-rsfMRI的时间信噪比（tSNR）。我们从图论测量角度观察语言网络连接性和小世界网络特征，以比较这两种技术。
我们计算了传统静息态功能磁共振成像（rsfMRI）和MB-rsfMRI技术的tSNR。MB-rsfMRI与传统rsfMRI的图论测量之间存在强正相关（皮尔逊相关系数，r = 0.99）。在健康对照中，两种技术均显示出相似的小世界网络特征。
本研究表明，在计算得到的图论测量方面，传统rsfMRI与MB-rsfMRI采集之间的差异可忽略不计。因此，当前分析证明，MB-rs-fMRI可作为一种缩短时间的采集技术，在健康受试者中能够绘制出与传统rs-fMRI结果相似的功能连接图。
