遗传镶嵌技术在心血管研究中的应用
Genetic Mosaics for Greater Precision in Cardiovascular Research.
机构信息
From the Department of Cardiology, Boston Children's Hospital, MA.
出版信息
Circ Res. 2018 Jun 22;123(1):27-29. doi: 10.1161/CIRCRESAHA.118.313386.
Abstract
Interpretation of cardiac gain- and loss- of function experiments are prone to secondary, indirect effects that confound and obscure data interpretation. We advocate the use of a genetic mosaic strategy to circumvent these issues and increase precision in cardiovascular research.
摘要
心脏功能增益和损失实验的解读容易受到二次、间接效应的干扰，从而混淆和模糊数据解读。我们主张使用基因镶嵌策略来规避这些问题，提高心血管研究的精度。
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